Document Detail

The effect of peritonitis on the peritoneal membrane transport properties in patients on CAPD.
MedLine Citation:
PMID:  8865897     Owner:  NLM     Status:  MEDLINE    
Peritonitis is known to acutely affect the transport characteristics of the peritoneal membrane, however, the long-term effects are not known. We studied the effect of peritoneal inflammation on mean dialysate-to-plasma creatinine concentration ratio (D/P), dialysate protein losses (DPL, g/week), and dialysate albumin losses (DAL, g/week), done at six weeks or more postepisode, in 152 patients [102 (67%) males, mean age 57 years (range 21-91)]. These patients were on continuous ambulatory peritoneal dialysis for a mean of twelve months (range 1-97). A total of 94 distinct peritonitis episodes were managed in 47 patients (31%). The number of patients with 0, 1, 2, 3, 4, and 5 episodes of peritonitis were 105, 29, 3, 6, 4, and 5. These episodes were treated with a standard protocol. There were no statistically significant differences between the D/P, DPL, or DAL between the groups. The parameters did not show any correlation to time on dialysis. Thus, in conclusion, peritonitis, if promptly treated, does not cause any permanent change in D/P, DAL, or DPL.
S Goel; P Kathuria; H L Moore; B F Prowant; K D Nolph
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Advances in peritoneal dialysis. Conference on Peritoneal Dialysis     Volume:  12     ISSN:  1197-8554     ISO Abbreviation:  Adv Perit Dial     Publication Date:  1996  
Date Detail:
Created Date:  1997-01-30     Completed Date:  1997-01-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9104803     Medline TA:  Adv Perit Dial     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  181-4     Citation Subset:  IM    
Division of Nephrology, University of Missouri-Columbia, USA.
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MeSH Terms
Aged, 80 and over
Blood Proteins / metabolism*
Cell Membrane Permeability / physiology*
Creatinine / blood*
Kidney Failure, Chronic / physiopathology*,  therapy
Middle Aged
Peritoneal Dialysis, Continuous Ambulatory*
Peritonitis / physiopathology*
Serum Albumin / metabolism*
Reg. No./Substance:
0/Blood Proteins; 0/Serum Albumin; 60-27-5/Creatinine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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