Document Detail

The effect of peripherally inserted central catheter (PICC) valve technology on catheter occlusion rates - The 'ELeCTRiC' study.
MedLine Citation:
PMID:  22505280     Owner:  NLM     Status:  Publisher    
Purpose: Peripherally Inserted Central Catheters (PICCs) are increasingly being used to provide short to medium-term central venous access. The current study was designed to test the hypothesis that PICC valve technology does not influence PICC occlusion rates. Methods: Intensive care unit (ICU) patients who required a PICC were randomized to one of three types of dual lumen PICC (open ended non-valved, Groshong valve, PASV valve). PICC occlusions were recorded and managed with a protocol that used urokinase. Results: A total of 102 patients were recruited to the study. The overall risk of occlusion per catheter was 35% (95% CI 26% to 44%). The overall rate of occlusion was 76 occlusions per 1000 catheter days (95% CI 61 to 95). Presence or type of valve did not significantly influence this rate (open-ended non-valved PICC 38% of catheters, 79 occlusions per 1000 catheter days; Groshong 38% of catheters, 60 occlusions per 1000 catheter days; PASV 27% of catheters, 99 occlusions per 1000 catheter days). The dose of urokinase required to treat PICC occlusions did not significantly differ between PICC types. Conclusions: Valved PICCs do not appear to influence PICC occlusion rates.
Andrew J Johnston; Carmel T Streater; Remy Noorani; Joanne L Crofts; Aldwin B Del Mundo; Richard A Parker
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-4-2
Journal Detail:
Title:  The journal of vascular access     Volume:  -     ISSN:  1724-6032     ISO Abbreviation:  -     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-4-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100940729     Medline TA:  J Vasc Access     Country:  -    
Other Details:
Languages:  ENG     Pagination:  0     Citation Subset:  -    
Vascular Access Team, Cambridge University Hospitals NHS Foundation Trust, Cambridge and John Farman Intensive Care Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge - UK.
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