| The effect of parity and gravidity on the outcome of medical termination of pregnancy. | |
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MedLine Citation:
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PMID: 21090516 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Previous pregnancies may influence the success of medical termination of pregnancy. OBJECTIVES: To determine the effect of parity and gravidity on the successful termination of pregnancy using mifepristone and misoprostol. METHODS: The medical files of all patients attending a department of obstetrics and gynecology during the years 2006 and 2007 for the purpose of medical termination of pregnancy at < or = 49 days of gestation were analyze retrospectively. The medical history, previous pregnancies and deliveries were recorded. Mifepristone was administered orally followed by 400 mg of misoprostol 48 hours later. A second dose of misoprostol was offered 2 weeks later if uterine content thickness was more than 15 mm. Then, after 24 hours, if uterine content thickness was more than 15 mm the uterus was evacuated by dilation and curettage. RESULTS: Of 403 women, 349 (86.6%) aborted following the basic regime; 207 (51.4%) (group A) were primiparous while 196 (48.6%) (group B) had at least one prior pregnancy. Uterine curettage was performed in 17 patients (8.2%) in group A and in 37 (18.9%) in group B (P = 0.002). When patients with a history of a previous abortion were excluded from group B, 32 of 143 (22.4%) required curettage (P < 0.001). When patients without a history of previous cesarean section were excluded, 10 of 52 (19.2%) underwent curettage (P = 0.038). CONCLUSIONS: Previous pregnancies negatively affect the success of medical termination of pregnancy, especially in women with a previous term pregnancy. This information is important when counseling women about the method of pregnancy termination. |
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Authors:
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Marwan Odeh; Rene Tendler; Vladimir Sosnovsky; Mohamad Kais; Ella Ophir; Jacob Bornstein |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Israel Medical Association journal : IMAJ Volume: 12 ISSN: 1565-1088 ISO Abbreviation: Isr. Med. Assoc. J. Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-11-24 Completed Date: 2010-12-23 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100930740 Medline TA: Isr Med Assoc J Country: Israel |
Other Details:
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Languages: eng Pagination: 606-8 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, Western Galilee Hospital, Nahariya, Israel. marwan20@bezeqint.net |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abortifacient Agents Abortion, Induced* Adult Cohort Studies Female Gravidity* Humans Israel Mifepristone Misoprostol Parity* Pregnancy Retrospective Studies Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Abortifacient Agents; 59122-46-2/Misoprostol; 84371-65-3/Mifepristone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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