| The effect of oxygen exposure on erythrocyte phospholipid composition. | |
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MedLine Citation:
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PMID: 7330867 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Phospholipids in plasma and erythrocytes of rats exposed to 100% oxygen for 3 days were analyzed. Exposed rats contained lower quantities of several phospholipids in both plasma and erythrocytes than in matched controls. Pronounced decreases were found in phosphatidylcholine and lysophosphatidyl choline. The proportion of disaturated species in erythrocyte phosphatidylcholine was significantly greater after oxygen exposure. There was an increase in percentage of saturated fatty acids with a proportionate decrease in percentage of unsaturated fatty acids. The increase in saturation was associated primarily with palmitate while decreased unsaturation involved primarily linoleic acid. In plasma the proportions of stearic acid increased while those of linoleic, arachidonic and docosahexaenoic acids decreased in phosphatidylcholine. Damage to cell lipids may account for increased hemolysis which occurs after exposure to high oxygen concentrations. Erythrocytes recovered following oxygen exposure contained phospholipid species commonly found in immature red blood cells. |
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Authors:
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M Abe; A Sevanian |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Tohoku journal of experimental medicine Volume: 135 ISSN: 0040-8727 ISO Abbreviation: Tohoku J. Exp. Med. Publication Date: 1981 Oct |
Date Detail:
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Created Date: 1982-04-22 Completed Date: 1982-04-22 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0417355 Medline TA: Tohoku J Exp Med Country: JAPAN |
Other Details:
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Languages: eng Pagination: 205-11 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Blood Proteins / analysis Erythrocytes / analysis*, drug effects Fatty Acids / blood Linoleic Acids / blood Male Oxygen / adverse effects* Phosphatidylcholines / blood Phospholipids / blood* Rats |
| Chemical | |
Reg. No./Substance:
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0/Blood Proteins; 0/Fatty Acids; 0/Linoleic Acids; 0/Phosphatidylcholines; 0/Phospholipids; 7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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