Document Detail


The effect of orally administered androgens on sperm motility.
MedLine Citation:
PMID:  1116625     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The administration of oral androgens increased sperm motility to normal in 30 (52%) of 58 men whose impaired motility was the only defect in their semen quality. Their ejaculate volume, sperm count, and morphology were not benefited. Suppression was infrequently seen and appeared to be transient. Pregnancies were documented in 15 (26%) of the 58 couples studies. However, communication regarding this matter was made with only 39 of the 58 couples. The benefical effect from a single course of androgen is likely to persist. However, if a pregnancy does not ensue, semen analysis should be repeated to determine if additional medication is necessary. Pretreatment serum testosterone determinations were not helpful in determining those men who would most likely benefit from therapy. No appreciable benefit was noted in the semen quality of the 35 subfertile men identically treated who, in addition to poor sperm motility, had other defects in their semen.
Authors:
J S Brown
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Fertility and sterility     Volume:  26     ISSN:  0015-0282     ISO Abbreviation:  Fertil. Steril.     Publication Date:  1975 Apr 
Date Detail:
Created Date:  1975-06-12     Completed Date:  1975-06-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  305-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Administration, Oral
Adult
Androgens / administration & dosage*
Cell Count
Cell Movement / drug effects
Female
Fluoxymesterone / administration & dosage,  adverse effects,  therapeutic use
Follow-Up Studies
Gynecomastia / chemically induced
Humans
Infertility, Male / drug therapy
Male
Middle Aged
New York City
Pregnancy
Semen / analysis
Spermatozoa / drug effects*,  physiology
Testosterone / blood
Chemical
Reg. No./Substance:
0/Androgens; 58-22-0/Testosterone; 76-43-7/Fluoxymesterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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