Document Detail

The effect of oral ritodrine therapy on glucose tolerance in pregnancy.
MedLine Citation:
PMID:  4025449     Owner:  NLM     Status:  MEDLINE    
Intravenous ritodrine therapy can cause significant deterioration of maternal glucose homeostasis. We investigated the effect of full maintenance oral ritodrine therapy (120 mg/day) on glucose tolerance in the early third trimester with the use of 50 gm 1-hour screens followed by 100 gm 3-hour oral glucose tolerance tests if the screen level was greater than or equal to 140 mg/dl. Four hundred ninety-one patients were studied, 42 of whom were receiving oral ritodrine therapy. Twenty-one percent of the ritodrine-treated women had an abnormal 1-hour screen, which was not different from the 20% observed in women not receiving therapy. None of the treated group and 13% of the untreated group who had abnormal screens had abnormal oral glucose tolerance tests. The probability of an abnormal test after an abnormal 1-hour screen was also determined.
D M Main; E K Main; S E Strong; S G Gabbe
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  152     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1985 Aug 
Date Detail:
Created Date:  1985-09-24     Completed Date:  1985-09-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1031-3     Citation Subset:  AIM; IM    
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MeSH Terms
Administration, Oral
Blood Glucose / metabolism*
Glucose Tolerance Test
Hypertension / blood
Pregnancy Complications, Cardiovascular / blood
Pregnancy in Diabetics / blood
Propanolamines / pharmacology*
Ritodrine / administration & dosage,  pharmacology*
Reg. No./Substance:
0/Blood Glucose; 0/Propanolamines; 26652-09-5/Ritodrine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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