Document Detail

The effect of oral doxantrazole on allergen-induced bronchospasm.
MedLine Citation:
PMID:  821299     Owner:  NLM     Status:  MEDLINE    
The protective effect of 200 mg doxantrazole given orally on allergen-induced bronchoconstriction has been compared with 20 mg inhaled disodium cromoglycate (DSCG) in 15 patients with bronchial asthma and immediate-type hypersensitivity. Only four out of the 15 patients showed a significant inhibition of their bronchoconstriction after the oral intake of doxantrazole. Nine patients were significantly protected by 20 mg DSCG. All patients responding to doxantrazole also responded well to DSCG.
R Pauwels; H Lamont; M van der Straeten
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Acta allergologica     Volume:  31     ISSN:  0001-5148     ISO Abbreviation:  Acta Allergol     Publication Date:  1976 Jun 
Date Detail:
Created Date:  1976-10-01     Completed Date:  1976-10-01     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370567     Medline TA:  Acta Allergol     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  239-44     Citation Subset:  IM    
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MeSH Terms
Administration, Oral
Azoles / therapeutic use*
Bronchial Spasm / drug therapy*,  etiology,  physiopathology
Cromolyn Sodium / therapeutic use
Drug Evaluation
Forced Expiratory Volume
Tetrazoles / administration & dosage,  therapeutic use*
Reg. No./Substance:
0/Allergens; 0/Azoles; 0/Tetrazoles; 15826-37-6/Cromolyn Sodium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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