Document Detail


The effect of oral doxantrazole on allergen-induced bronchospasm.
MedLine Citation:
PMID:  821299     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The protective effect of 200 mg doxantrazole given orally on allergen-induced bronchoconstriction has been compared with 20 mg inhaled disodium cromoglycate (DSCG) in 15 patients with bronchial asthma and immediate-type hypersensitivity. Only four out of the 15 patients showed a significant inhibition of their bronchoconstriction after the oral intake of doxantrazole. Nine patients were significantly protected by 20 mg DSCG. All patients responding to doxantrazole also responded well to DSCG.
Authors:
R Pauwels; H Lamont; M van der Straeten
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Acta allergologica     Volume:  31     ISSN:  0001-5148     ISO Abbreviation:  Acta Allergol     Publication Date:  1976 Jun 
Date Detail:
Created Date:  1976-10-01     Completed Date:  1976-10-01     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370567     Medline TA:  Acta Allergol     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  239-44     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Administration, Oral
Adolescent
Adult
Allergens
Azoles / therapeutic use*
Bronchial Spasm / drug therapy*,  etiology,  physiopathology
Cromolyn Sodium / therapeutic use
Drug Evaluation
Female
Forced Expiratory Volume
Humans
Male
Tetrazoles / administration & dosage,  therapeutic use*
Chemical
Reg. No./Substance:
0/Allergens; 0/Azoles; 0/Tetrazoles; 15826-37-6/Cromolyn Sodium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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