| The effect of oral aluminium therapy on plasma aluminium levels in patients with chronic renal failure in an area with low water aluminium. | |
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MedLine Citation:
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PMID: 7094439 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In a low water aluminium area ( less than or equal to 0.4 micromoles/1) plasma aluminium levels were normal in 31 non-dialyzed and 7 peritoneally-dialyzed patients unless oral aluminium hydroxide was prescribed. Plasma aluminium levels were above normal in 26 patients on maintenance hemodialysis, but when aluminium hydroxide intake stopped there was a decrease in pre-dialysis plasma aluminium. Poor compliers (indicated by plasma phosphate levels) showed no change. Oral aluminium hydroxide can make a major contribution to plasma aluminium levels in patients with renal failure and should be treated with the same caution as high dialyzate aluminium. Post-dialysis plasma aluminium levels were always higher than pre-dialysis levels both on and off aluminium therapy despite the low dialyzate aluminium concentration. This rise may be due to tissue redistribution. |
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Authors:
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L W Fleming; W k Stewart; G S Fell; D J Halls |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Clinical nephrology Volume: 17 ISSN: 0301-0430 ISO Abbreviation: Clin. Nephrol. Publication Date: 1982 May |
Date Detail:
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Created Date: 1982-09-17 Completed Date: 1982-09-17 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0364441 Medline TA: Clin Nephrol Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 222-7 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Oral Aluminum / analysis, blood* Aluminum Hydroxide / administration & dosage* Great Britain Humans Kidney Failure, Chronic / blood*, drug therapy Renal Dialysis Water Supply / analysis* |
| Chemical | |
Reg. No./Substance:
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21645-51-2/Aluminum Hydroxide; 7429-90-5/Aluminum |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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