| The effect of obesity on mid-term survival following coronary artery bypass surgery. | |
| | |
MedLine Citation:
|
PMID: 12614808 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: Several studies have shown no significantly increased risk of in-hospital mortality for obese patients after coronary artery bypass grafting (CABG). However, the effect of obesity on mid-term survival has not been adequately studied. We set out to examine whether mid-term survival following CABG is affected by obesity. METHODS: We performed a retrospective study of 4713 consecutive patients undergoing isolated CABG between April 1997 and September 2001. Body mass index (BMI) was used as the measure of obesity, with 3429 patients categorised as non-obese (BMI<30 kg/m(2)), and 1284 patients as obese (BMI> or = 30 kg/m(2)). Patient records were linked to the National Strategic Tracing Service, which records all deaths in the community, to establish current vital status. Deaths occurring over time were described using Kaplan-Meier techniques. To control for differences in patient characteristics, we used Cox proportional hazards analysis to calculate adjusted hazard ratios (HR) and 95% confidence intervals (CI). RESULTS: Three hundred and thirty (7.0%) deaths occurred during the study period, with a mean follow-up of 2.4+/-1.4 years. The crude HR of mid-term mortality for obese patients was 1.09 (95% CI 0.86-1.39; P=0.457). After adjustment for core pre-operative factors, the adjusted HR of mid-term mortality for obese patients was 1.28 (95% CI 1.01-1.64; P=0.048). The adjusted freedom from death in the obese patients at 30 days, 1, 2, 3, and 4 years was 97.9, 95.9, 94.2, 92.4 and 90.5%, respectively, compared with 98.4, 96.8, 95.5, 94.0 and 92.5% for the non-obese patients. CONCLUSIONS: Although in-hospital mortality after CABG does not seem to be adversely affected by obesity there appears to be a significant increase in mortality in obese patients during a 4-year follow-up period. |
| | |
Authors:
|
Manoj Kuduvalli; Antony D Grayson; Aung Y Oo; Brian M Fabri; Abbas Rashid |
Related Documents
:
|
17658018 - Follow-up of roux-en-y gastric bypass patients at 5 or more years postoperatively. 21612448 - Comparison of results of laparoscopic gastric banding and consecutive intragastric ball... 15791368 - Laparoscopic colorectal surgery in obese and nonobese patients: do differences in body ... 18438618 - Severe recurrent hypoglycemia after gastric bypass surgery. 22596038 - Impact of magnitude and percentage global sagittal plane correction on health related q... 19561928 - The effect of age on the outcome of esophageal cancer surgery. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery Volume: 23 ISSN: 1010-7940 ISO Abbreviation: Eur J Cardiothorac Surg Publication Date: 2003 Mar |
Date Detail:
|
Created Date: 2003-03-04 Completed Date: 2003-07-03 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 8804069 Medline TA: Eur J Cardiothorac Surg Country: England |
Other Details:
|
Languages: eng Pagination: 368-73 Citation Subset: IM |
Affiliation:
|
Department of Cardiothoracic Surgery,The Cardiothoracic Centre, Liverpool, UK. arashid@ccl-tr.nwest.nhs.uk |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Body Mass Index Coronary Artery Bypass / mortality* England / epidemiology Epidemiologic Methods Female Humans Male Medical Record Linkage Middle Aged Obesity / complications* Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Early and late outcome of myocardial revascularization with and without cardiopulmonary bypass in hi...
Next Document: Chest injury due to blunt trauma.