Document Detail


The effect of norepinephrine, isoprenaline and acetylcholine on the testicular and epididymal circulation in the pig.
MedLine Citation:
PMID:  6840879     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Blood flow to the testis and epididymis of 7 anaesthetized male pigs was measured using electromagnetic blood flow sensors. An average blood flow to the testis of 12 ml/min/100 g and in the epididymal arteries of 19 ml/min/100 g was measured. The effect of intravenously administered norepinephrine, isoprenaline and acetylcholine on alpha and beta 2 adrenergic and cholinergic receptor sites, respectively, was investigated. As neither norepinephrine nor isoprenaline, nor acetylcholine changed vascular conductance of the testis, we could not demonstrate adrenergic and cholinergic receptor activity. The possibility of autonomic regulation by the nonvascular smooth muscles of the spermatic cord and the inner layer of the tunica albuginea has been discussed.
Authors:
E N Noordhuizen-Stassen; H J Beijer; G A Charbon; C J Wensing
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  International journal of andrology     Volume:  6     ISSN:  0105-6263     ISO Abbreviation:  Int. J. Androl.     Publication Date:  1983 Feb 
Date Detail:
Created Date:  1983-06-10     Completed Date:  1983-06-10     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8000141     Medline TA:  Int J Androl     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  44-56     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Acetylcholine / pharmacology*
Animals
Blood Pressure / drug effects
Epididymis / blood supply*
Heart Rate / drug effects
Isoproterenol / pharmacology*
Male
Norepinephrine / pharmacology*
Regional Blood Flow / drug effects
Swine
Testis / blood supply*
Chemical
Reg. No./Substance:
51-41-2/Norepinephrine; 51-84-3/Acetylcholine; 7683-59-2/Isoproterenol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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