Document Detail

The effect of the non-steroidal anti-inflammatory drug choline magnesium trisalicylate on gastric mucosal cell exfoliation.
MedLine Citation:
PMID:  6691886     Owner:  NLM     Status:  MEDLINE    
Gastric mucosal cell exfoliation was measured in 10 normal subjects taking choline magnesium trisalicylate (CMT), aspirin and placebo. Both drugs resulted in significantly elevated rates of exfoliation although the serum salicylate levels achieved with aspirin were lower than those achieved by CMT. Side-effects of tinnitus, nausea and increased faecal blood loss were more common while subjects were taking CMT.
K G Mitchell; J Hearns; G P Crean
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  British journal of clinical pharmacology     Volume:  17     ISSN:  0306-5251     ISO Abbreviation:  Br J Clin Pharmacol     Publication Date:  1984 Jan 
Date Detail:
Created Date:  1984-03-06     Completed Date:  1984-03-06     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  7503323     Medline TA:  Br J Clin Pharmacol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  27-30     Citation Subset:  IM    
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MeSH Terms
Aspirin / adverse effects
Choline / adverse effects,  analogs & derivatives*
Gastric Mucosa / cytology,  drug effects*
Random Allocation
Salicylates / adverse effects*
Salicylic Acid
Salicylic Acids / blood
Reg. No./Substance:
0/Salicylates; 0/Salicylic Acids; 50-78-2/Aspirin; 62-49-7/Choline; 64425-90-7/choline magnesium trisalicylate; 69-72-7/Salicylic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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