Document Detail


The effect of the non-steroidal anti-inflammatory drug choline magnesium trisalicylate on gastric mucosal cell exfoliation.
MedLine Citation:
PMID:  6691886     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Gastric mucosal cell exfoliation was measured in 10 normal subjects taking choline magnesium trisalicylate (CMT), aspirin and placebo. Both drugs resulted in significantly elevated rates of exfoliation although the serum salicylate levels achieved with aspirin were lower than those achieved by CMT. Side-effects of tinnitus, nausea and increased faecal blood loss were more common while subjects were taking CMT.
Authors:
K G Mitchell; J Hearns; G P Crean
Related Documents :
23095256 - Pharmacophore-based drug design and biological evaluation of novel abcb1 inhibitors.
23468946 - High expression of lewis y antigen and cd44 is correlated with resistance to chemothera...
24449076 - In situ floating hydrogel for intravesical delivery of adriamycin without blocking urin...
285986 - Aspirin idiosyncrasy.
962496 - The pro-heroin effects of anti-opium laws in asia.
11727966 - Compliance with prescription recommendations by physicians in practices.
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  British journal of clinical pharmacology     Volume:  17     ISSN:  0306-5251     ISO Abbreviation:  Br J Clin Pharmacol     Publication Date:  1984 Jan 
Date Detail:
Created Date:  1984-03-06     Completed Date:  1984-03-06     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  7503323     Medline TA:  Br J Clin Pharmacol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  27-30     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Aspirin / adverse effects
Choline / adverse effects,  analogs & derivatives*
Female
Gastric Mucosa / cytology,  drug effects*
Humans
Male
Random Allocation
Salicylates / adverse effects*
Salicylic Acid
Salicylic Acids / blood
Chemical
Reg. No./Substance:
0/Salicylates; 0/Salicylic Acids; 50-78-2/Aspirin; 62-49-7/Choline; 64425-90-7/choline magnesium trisalicylate; 69-72-7/Salicylic Acid
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Information, compliance and side-effects: a study of patients on antidepressant medication.
Next Document:  Central effects of single oral doses of propranolol in man.