Document Detail


The effect of a new anti-allergic drug ICI 74, 9I7, given by aerosol, on nasal stenosis induced by allergen.
MedLine Citation:
PMID:  975489     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Nasal airways resistance was measured in ten patients with allergic rhinitis during intranasal application of an extract of grass pollen. Pretreatment with placebo did not inhibit the increase in nasal airways resistance, whereas ICI 74,917 administered from a pressurized aerosol gave almost complete protection. ICI 74,917 was well tolerated and no evidence was obtained of local hyposensitization during the period of the study.
Authors:
J S Vilsvik; A O Jenssen
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Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Clinical allergy     Volume:  6     ISSN:  0009-9090     ISO Abbreviation:  Clin. Allergy     Publication Date:  1976 Sep 
Date Detail:
Created Date:  1976-12-30     Completed Date:  1976-12-30     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0311172     Medline TA:  Clin Allergy     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  487-91     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aerosols
Airway Resistance
Female
Humans
Male
Phenanthrolines / therapeutic use*
Poaceae / immunology
Pollen / immunology
Rhinitis, Allergic, Seasonal / drug therapy*
Chemical
Reg. No./Substance:
0/Aerosols; 0/Phenanthrolines

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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