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The effect of the neonatal resuscitation courses on the long-term neurodevelopmental outcomes of newborn infants with perinatal asphyxia*
MedLine Citation:
PMID:  21895865     Owner:  NLM     Status:  Publisher    
Background:  In previous studies, it has been demonstrated that Neonatal Resuscitation Program (NRP) courses improve the early outcomes of infants with perinatal asphyxia, however there has been no evidence to demonstrate the effect of NRP on long-term outcomes of perinatal asphyxia. The goal of this study was to determine the effect of the NRP courses on the long-term neurodevelopmental outcome of perinatal asphyxia. Methods:  This prospective study included infants referred to our Neonatal Unit during the years of 2003-2005. Those patients who were referred before NRP courses (pretraining period) were designated as Group 1, those who were referred after the first NRP course (transition period) as Group 2, and those who were referred after the second NRP course (posttraining period) as Group 3. Neurodevelopmental outcomes were assessed and compared at 4-6 years of age. Results:  The study comprised 40 patients; 23 in Group 1, 9 in Group 2 and 8 in Group 3. The number of patients who had been diagnosed as cerebral palsy was 13 in Group 1, 2 in Group 2, and 1 in Group 3 which decreased significantly. The number of patients with seizures and EEG abnormality was 12 and 14 in Group 1, 3 and 2 in Group 2, 1 and 1 in Group 3 respectively which also decreased significantly. Conclusions:  NRP courses have positive effects on early as well as long-term neurodevelopmental outcomes of infants with perinatal asphyxia. Further studies are required for determining the effects of NRP courses on minor deficits, such as cognitive and behavioral disturbances.
Rıdvan Duran; Işık Görker; Yasemin Küçükuğurluoğlu; Nükhet Aladağçıftdemır; Ulfet Vatansever Özbek; Betül Acunaş
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-9-5
Journal Detail:
Title:  Pediatrics international : official journal of the Japan Pediatric Society     Volume:  -     ISSN:  1442-200X     ISO Abbreviation:  -     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-9-7     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100886002     Medline TA:  Pediatr Int     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2011 The Authors. Pediatrics International © 2011 Japan Pediatric Society.
Departments of Pediatrics and Child and Adolescent Psychiatry, Trakya University Faculty of Medicine, Edirne, Turkey.
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