Document Detail


The effect of nasal structure on olfactory function in patients with OSA.
MedLine Citation:
PMID:  24890976     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The aim of this study was to investigate the relationship between nasal structure and olfactory function in patients with obstructive sleep apnea (OSA). Olfaction and nasal structure of 76 adults with OSA diagnosed by polysomnography were measured using acoustic rhinometry and the Sniffin, Sticks (SS) smell test at Anzhen Hospital, a major academic center in Beijing, China. We tested the hypothesis that nasal structure in these patients would correlate with objectively measured olfactory performance. Minimum cross-sectional area (MCA) of the nose was significantly correlated with SS composite score (r = 0.434, p < 0.001), a result that was driven by two of the test's three components: olfactory threshold (OT) (r = 0.385, p = 0.001) and olfactory discrimination (OD) (r = 0.370, p = 0.001) but not olfactory identification (OI) (p > 0.05). Additionally, nasal volume (NV) was associated with composite SS score (r = 0.350, p = 0.002), a finding driven by OT (r = 0.283, p = 0.014). These data suggest that nasal structure affects parameters of olfactory function, likely via alterations in nasal airflow. Thus, anatomic abnormalities and diseases involving airflow (such as OSA) may cause, in part, olfactory dysfunction that is amenable to treatment. We speculate that surgery that alters nasal volume and MCA may improve olfactory performance.
Authors:
Dan Fu; Jayant M Pinto; Li Wang; Guowei Chen; Xiaojun Zhan; Yongxiang Wei
Related Documents :
22558646 - Atypical presentation of subclinical rhythmic electrographic discharge of adults (sreda...
25227246 - Serotonergic correlation with anger and aggressive behavior in acute stroke patients: a...
25258016 - Evaluation of the recombinant tissue plasminogen activator pretreatment in acute stroke...
9709566 - Personality characteristics of temporomandibular disorder patients using m.m.p.i.
15256186 - Auditory event-related potentials (p300) in the identification of psychogenic nonepilep...
9272706 - Scintigraphic evaluation of tc-99m-low-density lipoprotein (ldl) distribution in patien...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-6-3
Journal Detail:
Title:  European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery     Volume:  -     ISSN:  1434-4726     ISO Abbreviation:  Eur Arch Otorhinolaryngol     Publication Date:  2014 Jun 
Date Detail:
Created Date:  2014-6-3     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9002937     Medline TA:  Eur Arch Otorhinolaryngol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Evolution of alternative male morphotypes in oxyurid nematodes: a case of convergence?
Next Document:  Treatment of patients with anaplastic thyroid cancer during the last 20 years: whether any progress ...