Document Detail

The effect of n-3 fatty acids on low density lipoprotein subfractions.
MedLine Citation:
PMID:  11837999     Owner:  NLM     Status:  MEDLINE    
A predominance of small, dense low density lipoprotein (LDL) represents a significant source of increased risk for the development of coronary heart disease in Westernized countries. Dietary long-chain n-3 polyunsaturated fatty acids exert a potent triglyceride-lowering effect that redistributes LDL subfractions toward larger and lighter particles. These dietary fatty acids thus have a key role to play in providing protection against this particularly atherogenic type of LDL.
B A Griffin
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Lipids     Volume:  36 Suppl     ISSN:  0024-4201     ISO Abbreviation:  Lipids     Publication Date:  2001  
Date Detail:
Created Date:  2002-02-11     Completed Date:  2002-07-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0060450     Medline TA:  Lipids     Country:  United States    
Other Details:
Languages:  eng     Pagination:  S91-7     Citation Subset:  IM    
Centre for Nutrition & Food Safety, School of Biomedical & Life Sciences, University of Surrey, Guildford,United Kingdom.
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MeSH Terms
Apolipoproteins E / genetics
Cholesterol, LDL / blood
Coronary Disease / blood,  epidemiology
Fatty Acids, Omega-3 / administration & dosage,  pharmacology*
Fish Oils / administration & dosage
Lipoproteins / blood
Lipoproteins, LDL / blood*
Polymorphism, Genetic
Risk Factors
Triglycerides / blood
Reg. No./Substance:
0/Apolipoproteins E; 0/Cholesterol, LDL; 0/Fatty Acids, Omega-3; 0/Fish Oils; 0/Lipoproteins; 0/Lipoproteins, LDL; 0/Triglycerides

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