Document Detail

The effect of multiple pregnancies on lumbar bone mineral density in Japanese women.
MedLine Citation:
PMID:  12200655     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To elucidate the effect of multiple pregnancies on lumbar spine bone mineral density (BMD). METHODS: The BMD of the lumbar spines (L2-L4) of 1,113 healthy women was measured within 7 days of childbirth. In addition 113 women had spine BMD measurements after their next delivery. RESULTS: In the cross-sectional study, there was no apparent effect of parity on lumbar BMD. In the longitudinal study, the mean BMD after the next delivery was significantly higher than that after the initial delivery (1.019 +/- 0.115 g/cm(2) vs. 1.006 +/- 0.117 g/cm(2), P = 0.001, paired t test) with a percent change (DeltaBMD%) of 1.4 +/- 4.2%. Multiple regression analysis to identify independent predictors of DeltaBMD% showed a negative correlation with maternal age at the subsequent delivery (P = 0.033) but no correlation of DeltaBMD% with the length of lactation between the scans. CONCLUSION: Multiple pregnancies may not reduce maternal lumbar BMD, although the percentage decrease in BMD was greater in older women at the subsequent delivery. The length of lactation between the scans had no effect on these results.
H Matsushita; T Kurabayashi; M Tomita; A Honda; K Takakuwa; K Tanaka
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Publication Detail:
Type:  Journal Article     Date:  2002-06-05
Journal Detail:
Title:  Calcified tissue international     Volume:  71     ISSN:  0171-967X     ISO Abbreviation:  Calcif. Tissue Int.     Publication Date:  2002 Jul 
Date Detail:
Created Date:  2002-08-29     Completed Date:  2003-03-04     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7905481     Medline TA:  Calcif Tissue Int     Country:  United States    
Other Details:
Languages:  eng     Pagination:  10-3     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Niigata University School of Medicine, 1-757 Asahimachi-dori, Niigata 951-8510, Japan.
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MeSH Terms
Body Weight
Bone Density / physiology*
European Continental Ancestry Group
Lumbar Vertebrae / physiology*
Middle Aged
Pregnancy, Multiple / physiology*
Weight Gain

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