Document Detail

The effect of maternal fish oil supplementation during the last trimester of pregnancy on blood pressure, heart rate and heart rate variability in the 19-year-old offspring.
MedLine Citation:
PMID:  22313729     Owner:  NLM     Status:  Publisher    
Studies in experimental animals and human subjects have suggested that intake of n-3 fatty acids in early life can affect cardiovascular risk factors in adult life. Therefore, the aim of the present study was to investigate the effect of fish oil (FO) supplementation during the third trimester of pregnancy on blood pressure (BP), heart rate (HR) and HR variability (HRV) in the 19-year-old offspring. The study was based on follow-up of a randomised, controlled trial from 1990, in which 533 pregnant women were randomised to FO, olive oil (OO) or no oil (NO) during the last trimester of pregnancy. The offspring was invited to a physical examination including BP, HR and HRV measurements. A subgroup consisting of the offspring of mothers with a low baseline fish intake also had 24 h HRV determined. The OO group was used as reference and multiple linear regression modelling was used to compare the FO and OO groups. A total of 180 of the offspring from the FO and OO groups agreed to participate in the study (45 %). The adjusted difference between the FO and OO groups was 2 (95 % CI - 1, 4) mmHg in systolic and 1 (95 % CI 0, 3) mmHg in diastolic BP. The difference in HR was 1 (95 % CI - 2, 4). Also, HRV indices did not differ significantly between groups. Hence, FO supplementation during late pregnancy was not associated with offspring BP, HR and HRV during adolescence.
Dorte Rytter; Jeppe H Christensen; Bodil H Bech; Erik B Schmidt; Tine B Henriksen; Sjurdur F Olsen
Related Documents :
19404899 - Warfarin-associated fetal intracranial hemorrhage in woman with mitral valve replacemen...
10217099 - Thrombosis in pregnancy: maternal and fetal issues.
22309709 - Heavy metals and couple fecundity, the life study.
22503519 - Perinatal outcome in cases of latent syphilis during pregnancy.
12066949 - Placental massive perivillous fibrin deposition associated with antiphospholipid antibo...
22710379 - Cerebral cavernous malformations and pregnancy: hemorrhage risk and influence on obstet...
17346529 - Increased recurrence of preterm delivery with early cessation of 17-alpha-hydroxyproges...
1806469 - Human placental 17 beta-estradiol dehydrogenase: enzymatic activity in the last weeks o...
678599 - Fetal pepsinogens in human amniotic fluid.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-2-7
Journal Detail:
Title:  The British journal of nutrition     Volume:  -     ISSN:  1475-2662     ISO Abbreviation:  -     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-2-8     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372547     Medline TA:  Br J Nutr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  1-9     Citation Subset:  -    
Section for Epidemiology, Department of Public Health, Aarhus University, Bartholins Allé 2, DK-8000 Aarhus C, Denmark.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Severe postpartum haemorrhage and mode of delivery: a retrospective cohort study.
Next Document:  TRPV1 antagonists may exacerbate sepsis in aged mice: Should we be nervous?