Document Detail

The effect of magnesium sulphate infusion on circulating catecholamine levels in severe gestational proteinuric hypertension. A report of 8 cases.
MedLine Citation:
PMID:  2251618     Owner:  NLM     Status:  MEDLINE    
The effect of magnesium sulphate (MgSO4) infusion on blood pressure and circulating venous catecholamine levels in 8 patients with severe gestational proteinuric hypertension is described. A significant fall in blood pressure was noted after MgSO4 infusion; the maximal fall in diastolic blood pressure correlated with the greatest rise in serum magnesium levels (P less than 0.04). No significant change was observed in mean venous plasma adrenaline or noradrenaline levels after MgSO4 infusion, although the mean dopamine concentration declined significantly. It is concluded that the decrease in systemic vascular resistance after MgSO4 infusion in gestational proteinuric hypertension is mediated predominantly by mechanisms other than a change in circulating catecholamine levels.
M J England; V R Panz; B I Joffe; R M Touyz; R Shires; H C Seftel
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde     Volume:  78     ISSN:  0256-9574     ISO Abbreviation:  S. Afr. Med. J.     Publication Date:  1990 Dec 
Date Detail:
Created Date:  1991-01-15     Completed Date:  1991-01-15     Revised Date:  2014-09-12    
Medline Journal Info:
Nlm Unique ID:  0404520     Medline TA:  S Afr Med J     Country:  SOUTH AFRICA    
Other Details:
Languages:  eng     Pagination:  688-90     Citation Subset:  IM    
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MeSH Terms
Blood Pressure / drug effects
Catecholamines / blood*
Hypertension / blood*
Magnesium Sulfate / pharmacology*
Pregnancy Complications, Cardiovascular / blood*
Prospective Studies
Proteinuria / blood*
Reg. No./Substance:
0/Catecholamines; 7487-88-9/Magnesium Sulfate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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