| The effect of low-dose remifentanil on the hemodynamic responses of endotracheal extubation. | |
MedLine Citation:
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PMID: 25415818 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Emergence from general anesthesia can be associated with coughing, agitation, and hemodynamic disturbances. Remifentanil may attenuate these responses. We have examined the effect of remifentanil on the hemodynamic response to the emergence from anesthesia and tracheal extubation. In a double-blind, randomized trial, we enrolled 50 adult patients undergoing abdominal surgery. All patients received a standard general anesthetic comprising propofol, atracurium and 1% isoflurane with 50% nitrous oxide in oxygen. At the end of surgery, a bolus dose of remifentanil 0.2 microgram/kg (n = 25) or saline placebo (n = 25) was given and tracheal extubation was performed when standard criteria were achieved. Arterial pressure and heart rate were measured non-invasively, immediately after tracheal extubation and then at 1-min intervals. Remifentanil attenuated the increase in both systolic and diastolic arterial pressure and heart rate after extubation compared to the control group. No differences in SpO2, cough and laryngospasm were observed between two groups. Use of a low-dose remifentanil has clinically acceptable effect in blunting the cardiovascular changes induced by tracheal extubation. |
Authors:
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Alireza Mahoori; Heydar Noroozinia; Ebrahim Hasani; Nazli Karami; Nahid Pashaei; Sanaz Hatami |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta medica Iranica Volume: 52 ISSN: 1735-9694 ISO Abbreviation: Acta Med Iran Publication Date: 2014 Nov |
Date Detail:
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Created Date: 2014-11-22 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 14540050R Medline TA: Acta Med Iran Country: Iran |
Other Details:
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Languages: eng Pagination: 844-7 Citation Subset: IM |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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