Document Detail

The effect of limbic and extralimbic electrical stimulations upon prolactin secretion in humans.
MedLine Citation:
PMID:  3697759     Owner:  NLM     Status:  MEDLINE    
The effect that extra-hypothalamic regions of the brain have upon prolactin secretion in humans was evaluated by performing electrical stimulations. Thirty-nine stimulations were performed, 22 to basolateral amygdala, 12 to hippocampus and 5 to orbitofrontal, supplementary motor and cingulate cortex. Only two stimulations causing high-frequency widespread limbic afterdischarges were followed by significant prolactin elevation. Four low-frequency afterdischarges involving amygdala and anterior hippocampus, one amygdala stimulus-dependent discharge and 19 amygdala, 8 hippocampal and 5 frontal sub-afterdischarge threshold stimulations had no prolactin elevation. These results fail to replicate earlier studies. We suggest that there is no evidence that the amygdala regulates serum prolactin within physiologic ranges, but that the regulation of prolactin may depend primarily upon other sub-cortical structures.
M R Sperling; C L Wilson
Related Documents :
18164479 - The history and future of deep brain stimulation.
4001929 - Intracellular stimulation of an identified neuron evokes cardioacceleratory peptide rel...
21587289 - Microbes' roadmap to neurons.
2054659 - Antinociception produced by electrical stimulation of vagal afferents: independence of ...
17151229 - Cellular mechanisms underlying antiepileptic effects of low- and high-frequency electri...
19817809 - Preemptive effect of nucleus of the solitary tract stimulation on amygdaloid kindling i...
18241779 - The encephalopathy in sepsis.
23625819 - Botulinum toxin modulates cortical maladaptation in post-stroke spasticity.
25059569 - Preoptic inputs and mechanisms that regulate maternal responsiveness.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Brain research     Volume:  371     ISSN:  0006-8993     ISO Abbreviation:  Brain Res.     Publication Date:  1986 Apr 
Date Detail:
Created Date:  1986-06-18     Completed Date:  1986-06-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0045503     Medline TA:  Brain Res     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  293-7     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Amygdala / physiology
Electric Stimulation*
Frontal Lobe / physiology
Hippocampus / physiology
Hypothalamus / physiology*
Limbic System / physiology*
Prolactin / blood,  secretion*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  The neuroanatomical basis for the protopathic sensibility of the human glans penis.
Next Document:  Inhibition of jaw-closing muscles by electrical stimulation of the ophthalmic division in man.