Document Detail


The effect of left ventricular dysfunction on right ventricle ejection fraction during exercise in heart failure patients: Implications in functional capacity and blood pressure response.
MedLine Citation:
PMID:  19387959     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The aim of this study was to assess the effect of left ventricular dysfunction on right ventricular ejection fraction during exercise in heart failure patients and its implications in functional capacity and blood pressure response. METHODS: In a cross-sectional study 65 patients with heart failure were included. Left and right ventricular ejection fractions were evaluated by radio-isotopic ventriculography. All subjects underwent an exercise treadmill test (Bruce modified protocol). Systolic and diastolic blood pressures were also recorded. RESULTS: From the total population, 38 (58.46%) showed a significant increase (> or = 5%) in left ventricular ejection fraction (LVEF) and 27 (41.5%) showed a significant decrease in LVEF (> or = 5%) after the stress test. Patients with a significant reduction in LVEF during stress had lower exercise tolerance (4.1 +/- 2.5 vs. 6.1 +/- 2.5 METs, p = 0.009) compared to those who showed an increase in LVEF. Diastolic blood pressure was higher at rest among those who had a reduced LVEF during stress (83 +/- 12.2 vs. 72.6 +/- 12.2 mm Hg, p = 0.035) and during exercise (95 +/- 31.3 vs. 76.9 +/- 31.3 mm Hg, p = 0.057), as well as mean arterial pressure in the same group (97.1 +/- 11.6 mm Hg, p = 0.05). In addition, this group decrease of -8.8 +/- 51.6% in the right ventricular ejection fraction after exercise compared to an increase of 27.3 +/- +/- 49.1% (p = 0.007) among the patients with an increase in LVEF. CONCLUSIONS: Biventricular systolic dysfunction during exercise is associated with higher rest and stress blood pressure and worse functional capacity.
Authors:
Rubén Silva-Tinoco; Lilia Castillo-Martínez; Arturo Orea-Tejeda; Enrique Asensio-Lafuente; José Juan Orozco-Gutiérrez; Oscar Vázquez-Díaz; Verónica Rebollar-González
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cardiology journal     Volume:  16     ISSN:  1897-5593     ISO Abbreviation:  -     Publication Date:  2009  
Date Detail:
Created Date:  2009-04-23     Completed Date:  2009-06-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101392712     Medline TA:  Cardiol J     Country:  Poland    
Other Details:
Languages:  eng     Pagination:  127-32     Citation Subset:  IM    
Affiliation:
Heart Failure Clinic, Mexico City, México.
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MeSH Terms
Descriptor/Qualifier:
Blood Pressure*
Chronic Disease
Cross-Sectional Studies
Exercise Test
Exercise Tolerance*
Female
Heart Failure / complications*,  physiopathology,  radionuclide imaging
Humans
Male
Middle Aged
Radionuclide Ventriculography
Stroke Volume*
Ventricular Dysfunction, Left / etiology*,  physiopathology,  radionuclide imaging
Ventricular Dysfunction, Right / etiology*,  physiopathology,  radionuclide imaging

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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