Document Detail

The effect of isolated left bundle branch block on the myocardial velocities and myocardial performance index.
MedLine Citation:
PMID:  18307438     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: This study was planned in order to investigate the effect of left bundle branch block (LBBB) on myocardial velocities obtained by tissue Doppler echocardiography (TDE) and myocardial performance index (MPI). METHODS: Subjects with LBBB (n = 61) and age-matched healthy subjects (n = 60) were enrolled in the study. Left ventricular (LV) ejection fraction (EF), mitral inflow velocities (E-wave and A-wave), isovolumetric contraction and relaxation time (ICT and IRT), ejection time (ET), and flow propagation velocity (Vp) were measured by conventional echocardiography. Systolic velocity (Sm), early and late diastolic velocities (Em and Am) and time intervals were measured by TDE. MPI was calculated by the formula (ICT + IRT)/ET. RESULTS: LVEF and mitral E/A ratio were similar in both groups. Vp was lower in the LBBB group than in the control group, whereas the E/Em and the E/Vp ratio was higher. LV Sm and Em/Am ratio were lower in LBBB group. Right ventricular Sm and Em/Am ratio were similar in both groups. LV mean and RV MPI were significantly increased in LBBB group. CONCLUSION: These findings obtained by TDE show that isolated LBBB impairs the ventricular functions. Both of the LV and RV dysfunctions shown by the new parameters may contribute to increased morbidity and mortality in cases with isolated LBBB.
Mehmet Akif Duzenli; Kurtulus Ozdemir; Ahmet Soylu; Nazif Aygul; Mehmet Yazici; Mehmet Tokac
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Echocardiography (Mount Kisco, N.Y.)     Volume:  25     ISSN:  0742-2822     ISO Abbreviation:  Echocardiography     Publication Date:  2008 Mar 
Date Detail:
Created Date:  2008-02-29     Completed Date:  2008-06-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8511187     Medline TA:  Echocardiography     Country:  United States    
Other Details:
Languages:  eng     Pagination:  256-63     Citation Subset:  IM    
Department of Cardiology, Faculty of Medicine, Selcuk University, Konya, Turkey.
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MeSH Terms
Blood Flow Velocity*
Bundle-Branch Block / physiopathology*,  ultrasonography
Echocardiography, Doppler*
Middle Aged
Myocardial Contraction*
Stroke Volume
Ventricular Function, Left*

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