Document Detail

The effect of intravenous magnesium sulfate on acute postoperative bleeding in elective coronary artery bypass surgery.
MedLine Citation:
PMID:  20875883     Owner:  NLM     Status:  MEDLINE    
Postoperative blood drainage is a great concern for health care providers when monitoring patients after cardiac surgery. In this study, the effect of intravenous magnesium sulfate infusion on postoperative bleeding in patients undergoing elective coronary artery bypass graft (CABG) surgeries was assessed. In a double-blind, randomized placebo-controlled clinical trial, 140 patients scheduled for elective CABG were randomly assigned into two groups; one group receiving intravenous magnesium sulfate and one receiving placebo. All the cases were similar regarding anesthesia and surgery. The magnesium group had less postoperative bleeding (465 ± 130 mL vs 680 ± 190 mL in the placebo group; P = .00) and less packed cell use (2.1 ± 0.6 packs vs 3.2 ± 0.8 packs in the placebo group; P < .05) as compared with placebo. The results demonstrated significantly less postoperative bleeding and packed cell use in the group receiving intravenous magnesium sulfate infusion during elective CABG surgery.
Ali Dabbagh; Samira Rajaei; Mohammad Hasan Shamsolahrar
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses / American Society of PeriAnesthesia Nurses     Volume:  25     ISSN:  1532-8473     ISO Abbreviation:  J. Perianesth. Nurs.     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-09-29     Completed Date:  2011-01-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9610507     Medline TA:  J Perianesth Nurs     Country:  United States    
Other Details:
Languages:  eng     Pagination:  290-5     Citation Subset:  N    
Copyright Information:
Copyright © 2010 American Society of PeriAnesthesia Nurses. All rights reserved.
Anesthesiology Research Center, Shahid Beheshti University of Medicine, Tehran, Iran.
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MeSH Terms
Acute Disease
Calcium Channel Blockers / administration & dosage
Coronary Artery Bypass*
Erythrocyte Transfusion
Infusions, Intravenous
Magnesium Sulfate / administration & dosage*
Middle Aged
Postoperative Hemorrhage / prevention & control*
Reg. No./Substance:
0/Calcium Channel Blockers; 0/Placebos; 7487-88-9/Magnesium Sulfate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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