| The effect of intrauterine growth retardation on the expression of developmental factors in porcine placenta subsequent to the initiation of placentation. | |
| | |
MedLine Citation:
|
PMID: 20381143 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Intrauterine growth retardation (IUGR) hinders fetal growth and postnatal development in swine; however the etiology of IUGR is essentially unknown. Expression of fourteen candidate genes associated with placental development or IUGR was examined in gestational day 50 (gd50) control and IUGR fetus whole placental tissue or areolae by real-time PCR. Endothelial nitric oxide synthase (ENOS) mRNA expression was elevated in gd50 IUGR placenta and areola compared to gd50 control. Since ENOS could modulate vascular tone and angiogenesis via nitric oxide production, data suggest that the increase in IUGR may be an adaptive response to poor perfusion to maintain pregnancy. |
| | |
Authors:
|
L A Blomberg; L L Schreier; H David Guthrie; G L Sample; J Vallet; T Caperna; T Ramsay |
Related Documents
:
|
12175443 - Reduced red blood cell deformability, an indicator for high fetal or maternal risk, is ... 11980193 - Causes and consequences of fetal growth retardation in pigs. 15738033 - Prognostic value of umbilical artery doppler studies in unselected preterm deliveries. |
Publication Detail:
|
Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S. Date: 2010-04-08 |
Journal Detail:
|
Title: Placenta Volume: 31 ISSN: 1532-3102 ISO Abbreviation: Placenta Publication Date: 2010 Jun |
Date Detail:
|
Created Date: 2010-05-31 Completed Date: 2010-08-24 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8006349 Medline TA: Placenta Country: England |
Other Details:
|
Languages: eng Pagination: 549-52 Citation Subset: IM |
Affiliation:
|
Animal Biosciences and Biotechnology Laboratory, Animal and Natural Resources Institute, USDA Agricultural Research Service, Beltsville, MD 20705, USA. leann.blomberg@ars.usda.gov |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Female Fetal Growth Retardation / genetics*, metabolism Gene Expression Regulation, Developmental Nitric Oxide Synthase Type III / genetics*, metabolism Placenta / metabolism* Placentation / genetics* Pregnancy RNA, Messenger / genetics, metabolism Reverse Transcriptase Polymerase Chain Reaction Swine |
| Chemical | |
Reg. No./Substance:
|
0/RNA, Messenger; EC 1.14.13.39/Nitric Oxide Synthase Type III |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Abnormal expression of the imprinted gene Phlda2 in cloned bovine placenta.
Next Document: Biochemical biomarkers and metals in Perna perna mussels from mariculture zones of Santa Catarina, B...