Document Detail


The effect of intralipid on mononuclear and polymorphonuclear phagocytes.
MedLine Citation:
PMID:  6823887     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Eight healthy subjects were given Intralipid, a soybean oil emulsion, 20% intravenously for 2 h. During the infusion a significant increase in the nitroblue tetrazolium-reduction of blood monocytes was noted. Preincubation of monocytes in vitro with Intralipid (20 to 100 mg/ml) for 30 min was found to increase the ability of the cells to migrate chemotactically and to phagocytize yeast particles. On the contrary, when neutrophilic granulocytes were preincubated with Intralipid in the same concentrations for 30 min. their nitroblue-tetrazolium-reduction, chemotactic and spontaneous locomotion, as well as their ingestion of yeast particles was depressed.
Authors:
A Wiernik; C Jarstrand; I Julander
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The American journal of clinical nutrition     Volume:  37     ISSN:  0002-9165     ISO Abbreviation:  Am. J. Clin. Nutr.     Publication Date:  1983 Feb 
Date Detail:
Created Date:  1983-03-11     Completed Date:  1983-03-11     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376027     Medline TA:  Am J Clin Nutr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  256-61     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Chemotaxis, Leukocyte / drug effects
Fat Emulsions, Intravenous / pharmacology*
Female
Humans
Leukocyte Count
Male
Monocytes / drug effects*,  physiology
Neutrophils / drug effects*,  physiology
Phagocytosis / drug effects
Chemical
Reg. No./Substance:
0/Fat Emulsions, Intravenous

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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