Document Detail


The effect of interventional treatment in acute myocardial infarction on ST resolution: a comparison of coronary angioplasty with excimer laser angioplasty.
MedLine Citation:
PMID:  16079919     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The treatment methods for acute myocardial infarction (MI) have started to change in the new millennium. Myocardial perfusion (ST-segment resolution) is the target rather than achieving TIMI-III flow in the infarct-related artery. In this study the authors compared the effect of percutaneous transluminal coronary angioplasty (PTCA) and excimer laser angioplasty (ELCA), which was accepted as one of the thrombolysis methods, on ST-segment resolution. A stent was applied after ELCA to 36 patients (4 women, 32 men; mean age 50.44 +/-9.8 years) in group I and a stent was applied after balloon angioplasty to 44 patients (5 women, 39 men; mean age 50.77 +/-12.2 years) in group II. Fisher's exact test was used in the analysis of data, and p<0.05 was accepted as significant. There was no difference between the groups with respect to symptom duration, time to angioplasty, risk factors, infarct localization, stent diameter, and length. TIMI-III flow was achieved in 33 patients (92%) in group I and in 40 patients (91%) in group II. There was no statistical difference in TIMI flow between the groups. In group I, complete ST resolution was observed in 75% (27/36) of the patients, partial resolution in 22% (8/36), and resolution was unsuccessful in 3% (1/36). In group II, complete, partial, and unsuccessful ST resolution were 41% (18/44), 45% (20/44), and 14% (6/44), respectively. The mean ST resolution was 82.78 +/-11.8% in group I and 66.36 +/-10% in group II (p=0.001). ST segment resolution, which is a good predictor of tissue perfusion, was higher with ELCA than with balloon angioplasty. These findings should be supported by large randomized studies.
Authors:
Erdogan Ilkay; Ilgin Karaca; Mustafa Yavuzkir; Mehmet Akbulut; Murat Pekdemir
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Angiology     Volume:  56     ISSN:  0003-3197     ISO Abbreviation:  Angiology     Publication Date:    2005 Jul-Aug
Date Detail:
Created Date:  2005-08-04     Completed Date:  2005-09-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0203706     Medline TA:  Angiology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  377-84     Citation Subset:  IM    
Affiliation:
Firat University, Medical School, Department of Cardiology, Elaziğ, Turkey. ilkayerdogan@superonline.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Angioplasty, Balloon, Laser-Assisted*
Angioplasty, Transluminal, Percutaneous Coronary*
Female
Humans
Male
Middle Aged
Myocardial Infarction / physiopathology,  surgery,  therapy*
Stents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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