| The effect of insulin and hydrocortisone on the isolated rat liver. | |
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MedLine Citation:
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PMID: 285708 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Isolated rat livers were perfused at 35 degrees C with bovine serum albumin (40 g/l) in Krebs Ringer bicarbonate buffer, or with the same solution containing insulin (0.22 x 10(-6) mol/l), hydrocortisone (0.068 x 10(-3) mol/l), or both hormones together. Observations on the synthesis of bile and on perfusate levels of potassium, aspartate aminotransferase, urea and glucose showed that the presence of insulin and/or hydrocortisone had no beneficial effect on the perfused rat liver in vitro. There is little justification of the isolated liver. |
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Authors:
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A K Groufsky; R K Holland; D Lee |
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Publication Detail:
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Type: In Vitro; Journal Article |
Journal Detail:
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Title: The Australian and New Zealand journal of surgery Volume: 48 ISSN: 0004-8682 ISO Abbreviation: Aust N Z J Surg Publication Date: 1978 Oct |
Date Detail:
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Created Date: 1979-06-29 Completed Date: 1979-06-29 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0373115 Medline TA: Aust N Z J Surg Country: AUSTRALIA |
Other Details:
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Languages: eng Pagination: 575-80 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Aspartate Aminotransferases / secretion Bile / secretion Glucose / secretion Hydrocortisone / pharmacology* Insulin / pharmacology* Liver / drug effects*, enzymology, secretion Male Perfusion Potassium / secretion Rats Urea / secretion |
| Chemical | |
Reg. No./Substance:
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11061-68-0/Insulin; 50-23-7/Hydrocortisone; 50-99-7/Glucose; 57-13-6/Urea; 7440-09-7/Potassium; EC 2.6.1.1/Aspartate Aminotransferases |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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