Document Detail


The effect of hypohydration severity on the physiological, psychological and renal hormonal responses to hypoxic exercise.
MedLine Citation:
PMID:  19198872     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Evidence of the effect of dehydration on physiological responses to hypoxia is limited. The purpose of this study was to determine the effect of hypohydration severity on physiological, renal hormonal and psychological responses to acute hypoxia. Eight males completed intermittent walking tests under normobaric hypoxic conditions (FI O(2) = 0.13) after completing four separate hypohydration protocols, causing change in body mass of approximately 0% (EU), -1% (H1), -2% (H2) and -3% (H3). Physiological and psychological markers were monitored throughout the 125 min test. Fluid controlling hormones were measured pre and post exposure. Heart rate, core temperature, peripheral arterial oxygen saturation (SpO(2)), minute ventilation and urine osmolality were found to be significantly different between hydration conditions and correlated with Lake Louise Questionnaire score (LLQ) (P < 0.05). LLQ score increased with hypohydration severity above H2 (EU 1.3 +/- 1; H1 1.2 +/- 1; H2 2.7 +/- 2; H3 3.9 +/- 2) (P < 0.001). Antidiuretic hormone and aldosterone increased over the test, but were not different between hydration conditions (P < 0.05). Atrial natriuretic peptide showed no change over time, or with conditions. Therefore, renal hormones are not influenced by hypohydration severity during moderate intensity hypoxic exercise. Hypohydration less than -2% induces greater physiological strain during hypoxic exercise and may cause rise in symptoms such as, fatigue, headache, nausea and lightheadedness.
Authors:
Alan Richardson; Peter Watt; Neil Maxwell
Publication Detail:
Type:  Journal Article; Randomized Controlled Trial     Date:  2009-02-06
Journal Detail:
Title:  European journal of applied physiology     Volume:  106     ISSN:  1439-6327     ISO Abbreviation:  Eur. J. Appl. Physiol.     Publication Date:  2009 May 
Date Detail:
Created Date:  2009-04-22     Completed Date:  2009-07-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100954790     Medline TA:  Eur J Appl Physiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  123-30     Citation Subset:  IM    
Affiliation:
Chelsea School Research Centre, University of Brighton, Eastbourne, UK. a.j.richardson@brighton.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Adaptation, Physiological / physiology*
Adaptation, Psychological / physiology*
Adult
Aldosterone / urine
Algorithms
Body Weight / physiology
Dehydration / blood,  metabolism,  physiopathology*,  psychology
Exercise / physiology*
Heart Rate / physiology
Hormones / blood,  metabolism*,  urine
Humans
Kidney / metabolism
Male
Oxygen / physiology
Vasopressins / urine
Young Adult
Chemical
Reg. No./Substance:
0/Hormones; 11000-17-2/Vasopressins; 52-39-1/Aldosterone; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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