| The effect of hydrocortisone on the metabolism of PGE2 in rat lungs. | |
| | |
MedLine Citation:
|
PMID: 6960374 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Hydrocortisone pretreatment of male rats daily for five days (2 or 10 mg/kg, s.c.) had no significant effect on the total inactivation of prostaglandin E2 in isolated perfused rat lungs or on the activity of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase in the 100.000 x g supernatant fraction of homogenized lungs. Nor did pulmonary infusion of hydrocortisone (0.1 or 1 microM in the perfusion medium) have any effect on the metabolism of PGE2 in isolated rat lungs. The present study indicates that pulmonary inactivation of PGE2 is not changed by hydrocortisone in rat lungs. |
| | |
Authors:
|
T Puustinen; P Uotila |
Related Documents
:
|
6868084 - Inhalation of 1-nitropyrene associated with ultrafine insoluble particles or as a pure ... 3356194 - Tissue reaction following endobronchial application of iopamidol and ioxithalamate in r... 8200984 - Pertussis toxin treatment alters manganese superoxide dismutase activity in lung. evide... 8092844 - Aerosolized l-693,989 for pneumocystis carinii prophylaxis in rats. 8760204 - Transplantation of lean fetal hypothalamus restores hypothalamic function in zucker obe... 1248514 - The effect of corticosteroids and hemicholinium-3 on choline uptake and incorporation i... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
|
Title: Prostaglandins, leukotrienes, and medicine Volume: 9 ISSN: 0262-1746 ISO Abbreviation: Prostaglandins Leukot Med Publication Date: 1982 Nov |
Date Detail:
|
Created Date: 1983-02-25 Completed Date: 1983-02-25 Revised Date: 2007-11-14 |
Medline Journal Info:
|
Nlm Unique ID: 8206868 Medline TA: Prostaglandins Leukot Med Country: SCOTLAND |
Other Details:
|
Languages: eng Pagination: 479-82 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Dinoprostone Hydrocortisone / pharmacology* Lung / drug effects, metabolism* Male Prostaglandins E / metabolism* Rats Rats, Inbred Strains |
| Grant Support | |
ID/Acronym/Agency:
|
ES-016684-20/ES/NIEHS NIH HHS |
| Chemical | |
Reg. No./Substance:
|
0/Prostaglandins E; 363-24-6/Dinoprostone; 50-23-7/Hydrocortisone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Plasma 6-keto-prostaglandin F1 alpha in disorders involving hypokalemia.
Next Document: Anti-thromboxane A2 actions of pinane thromboxane A2 derivatives.