Document Detail

The effect of the herbal medicines dai-kenchu-to and keishi-bukuryo-gan on bowel movement after colorectal surgery.
MedLine Citation:
PMID:  15783004     Owner:  NLM     Status:  MEDLINE    
BACKGROUND/AIMS: To evaluate the safety and efficacy of the herbal medicines Dai-ken-chu-to and Keish-bukuryo-gan in the patients undergoing colorectal resection. METHODOLOGY: Sixty-six patients undergoing colorectal resection were studied. Patients in the Study group began on 7.5g of Dai-ken-chu-to and 6.0g of Keish-bukuryo-gan on the first postoperative day. Control group did not take herbal medicine at all. All of the patients were monitored for vomiting, abdominal distention, length of ileus, tolerance of regular diet, duration of intravenous fluid administration, length of hospitalization, and complications. RESULTS: The time to flatus was 63.1 +/- 22.8 hours and 95.4 +/- 33.0 hours in the Study and Control group, respectively (p<0.05). And the time to tolerance of regular diet was 2.53 +/- 1.93 days and 6.25 +/- 1.50 days in the Study and Control group, respectively (p<0.05). In addition, length of postoperative hospitalization in the patients within the Study group was significantly shorter than those within the Control group (15.7 +/- 4.8 days vs. 20.8 +/- 4.8 days, p<0.05). The incidence of complications including nausea, vomiting, anastomotic leak and wound infection occurred equally in both groups. CONCLUSIONS: Administration of Dai-ken-chu-to and Keish-bukuryo-gan is safe, with no evidence of increased morbidity, and is also highly effective in improving postoperative bowel motility and in reducing hospital stay.
Taketoshi Suehiro; Takashi Matsumata; Yasunori Shikada; Keizo Sugimachi
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Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  Hepato-gastroenterology     Volume:  52     ISSN:  0172-6390     ISO Abbreviation:  Hepatogastroenterology     Publication Date:    2005 Jan-Feb
Date Detail:
Created Date:  2005-03-23     Completed Date:  2005-07-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8007849     Medline TA:  Hepatogastroenterology     Country:  Greece    
Other Details:
Languages:  eng     Pagination:  97-100     Citation Subset:  IM    
Department of General Surgical Science, Graduate School of Medicine, Gunma University, Gunma, Japan.
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MeSH Terms
Colorectal Neoplasms / surgery*
Drugs, Chinese Herbal / pharmacology*
Eating / drug effects,  physiology
Gastrointestinal Motility / drug effects*,  physiology
Length of Stay
Middle Aged
Plant Extracts / pharmacology*
Postoperative Care
Reg. No./Substance:
0/Drugs, Chinese Herbal; 0/Plant Extracts; 0/dai-kenchu-to; 0/keishibukuryogan

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