Document Detail


The effect of heparin on endothelial stability.
MedLine Citation:
PMID:  6463964     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Heparin in ultra low doses had a stabilizing effect on endothelial lining in rats. This effect was demonstrated as prevention of increases in counts of circulating endothelial cells after a standard intravenous citrate injection. The same effect of heparin was observed even with other provoking agents /adrenaline, hypotonic saline/. The duration of heparin effect was very prolonged, a 50% effect having been observed 5 hours after the administration. Subcutaneous heparin was effective only in relatively high doses and had a lower maximum effect compared with intravenous heparin.
Authors:
J Hladovec
Related Documents :
12431484 - Effects of ximelagatran, the oral form of melagatran, in the treatment of caval vein th...
9386844 - Heparin clearance profiles after systemic anticoagulation using a heparin removal devic...
2863814 - 5-carboxylic derivatives of some 1,5-benzodiazepines.
10351964 - Abciximab facilitates the rate and extent of thrombolysis: results of the thrombolysis ...
20829054 - Antioxidative responses of elodea nuttallii (planch.) h. st. john to short-term iron ex...
8484264 - Pharmacokinetics of nefiracetam and three metabolites in humans and stereoselective hyd...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Thrombosis research     Volume:  35     ISSN:  0049-3848     ISO Abbreviation:  Thromb. Res.     Publication Date:  1984 Aug 
Date Detail:
Created Date:  1984-09-19     Completed Date:  1984-09-19     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0326377     Medline TA:  Thromb Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  347-52     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Blood Cell Count
Blood Vessels / drug effects
Citrates / toxicity
Endothelium / drug effects*
Epinephrine / toxicity
Female
Heparin / pharmacology*
Heparin Antagonists / pharmacology
Hypotonic Solutions / toxicity
Protamines / pharmacology
Rats
Vascular Diseases / chemically induced
Chemical
Reg. No./Substance:
0/Citrates; 0/Heparin Antagonists; 0/Hypotonic Solutions; 0/Protamines; 51-43-4/Epinephrine; 9005-49-6/Heparin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Platelet thrombus induced in vivo by filtered light and fluorescent dye in mesenteric microvessels o...
Next Document:  Roentgenologic studies of the spine in small domestic animals. 1. Routine studies