Document Detail

The effect of hemodialysis on cardiac rhythm and performance.
MedLine Citation:
PMID:  7249430     Owner:  NLM     Status:  MEDLINE    
The effects of hemodialysis on cardiac rhythm and left ventricular function were evaluated by Holter electrocardiographic monitoring and M-mode echocardiography in 22 stable patients on regular hemodialysis in hospital. Significant ventricular arrhythmias occurred in 9%. Mean left ventricular volume in diastole (LVVd) decreased significantly after dialysis from 156 +/- 12 ml to 135 +/- 9 ml (P less than 0.001). Similarly, mean left ventricular volume in systole (LVVs) decreased from 51 +/- 9 ml to 42 +/- 6 ml (P less than 0.025). Left ventricular function, as measured by mean velocity of circumferential fiber shortening (VCF), increased significantly for the entire group from 1.25 +/- 0.06 circ/sec to 1.38 +/- 0.06 circ/sec (P less than 0.05). Pre-dialysis VCF was normal in 15 patients (Group 1) and abnormal (less than 1.10 circ/sec) in 7 patients (Group 2). The mean VCF after VCF after dialysis did not change in Group 1 (1.40 +/- 0.05 circ/sec to 1.42 +/- 0.06 circ/sec, P = NS) but increased significantly in Group 2 (0.92 +/- 0.06 circ/sec to 1.29 +/- 0.12 circ/sec, P less than 0.005). There was no significant change in cardiac output or peripheral vascular resistance. Hemodialysis, when performed with careful potassium monitoring, has a low incidence of ventricular arrhythmias. In addition, hemodialysis reduces left ventricular volumes and improves overall cardiac performance in patients with abnormal left ventricular function predialysis.
I L Macdonald; R Uldall; A J Buda
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical nephrology     Volume:  15     ISSN:  0301-0430     ISO Abbreviation:  Clin. Nephrol.     Publication Date:  1981 Jun 
Date Detail:
Created Date:  1981-09-22     Completed Date:  1981-09-22     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0364441     Medline TA:  Clin Nephrol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  321-7     Citation Subset:  IM    
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MeSH Terms
Arrhythmias, Cardiac / etiology,  physiopathology*
Body Weight
Cardiac Output
Heart Function Tests
Heart Rate
Middle Aged
Renal Dialysis / adverse effects*

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