Document Detail

The effect of gestational age at birth on somatosensory-evoked potentials performed at term.
MedLine Citation:
PMID:  2246487     Owner:  NLM     Status:  MEDLINE    
Multimodality-evoked potentials are widely used in newborns to assess the maturation and integrity of the sensory pathways. Reliable normative data are needed to maximize the utility of this technique as a diagnostic and research tool. Several electrophysiologic studies on the maturational changes of the auditory brain-stem response have demonstrated that latency measurements decrease as a function of increasing conceptional age. However, maturational studies of the somatosensory-evoked potential, particularly in low-risk premature infants, are limited. The existing evoked potential literature in healthy newborns proposes that maturation of the central nervous system occurs at a predictable rate, irrespective of a given gestational age at birth. Behavioral studies of premature infants suggest that neurologic development may be altered by early extrauterine exposure. The purpose of this study was to determine whether brain-stem auditory- or somatosensory-evoked potential conduction times were comparable in premature and full-term infants matched for conceptional age. The results of this study suggest that myelination is determined by conceptional age, independent of premature birth.
A Majnemer; B Rosenblatt; D Willis; J Lavallee
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of child neurology     Volume:  5     ISSN:  0883-0738     ISO Abbreviation:  J. Child Neurol.     Publication Date:  1990 Oct 
Date Detail:
Created Date:  1991-01-10     Completed Date:  1991-01-10     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8606714     Medline TA:  J Child Neurol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  329-35     Citation Subset:  IM    
Evoked Potentials Laboratory, Montreal Children's Hospital, Quebec, Canada.
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MeSH Terms
Brain Stem / physiology*
Cohort Studies
Evoked Potentials, Auditory, Brain Stem / physiology*
Evoked Potentials, Somatosensory / physiology*
Follow-Up Studies
Gestational Age
Infant, Newborn
Infant, Premature / physiology*
Longitudinal Studies
Reference Values
Somatosensory Cortex / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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