Document Detail


The effect of free nitrous acid on the anabolic and catabolic processes of glycogen accumulating organisms.
MedLine Citation:
PMID:  20199792     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Nitrite/Free Nitrous Acid (FNA) has previously been shown to inhibit aerobic and anoxic phosphate uptake by polyphosphate accumulating organisms (PAOs). The inhibitory effect of FNA on the aerobic metabolism of Glycogen Accumulating Organisms (GAOs) is investigated. A culture highly enriched (92+/-3%) in Candidatus Competibacter phosphatis (hereafter called Competibacter) was used. The experimental data strongly suggest that FNA likely directly inhibits the growth of Competibacter, with 50% inhibition occurring at 1.5 x 10(-3)mgN-HNO(2)/L (equivalent to approximately 6.3 mgN-NO(2)(-)/L at pH 7.0). The inhibition is well described by an exponential function. The organisms ceased to grow at an FNA concentration of 7.1 x 10(-3) mgN-HNO(2)/L. At this FNA level, glycogen production, another anabolic process performed by GAOs in parallel to growth, decreased by 40%, while the consumption of polyhydroxyalkanoates (PHAs), the intracellular carbon and energy sources for GAOs, decreased by approximately 50%. FNA likely inhibited either or both of the PHA oxidation and glycogen production processes, but to a much less extent in comparison to the inhibition on growth. The comparison of these results with those previously reported on PAOs suggest that FNA has much stronger inhibitory effects on the aerobic metabolism of PAOs than on GAOs, and may thus provide a competitive advantage to GAOs over PAOs in enhanced biological phosphorus removal (EBPR) systems.
Authors:
Liu Ye; Maite Pijuan; Zhiguo Yuan
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-02-13
Journal Detail:
Title:  Water research     Volume:  44     ISSN:  1879-2448     ISO Abbreviation:  Water Res.     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-04-26     Completed Date:  2010-08-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0105072     Medline TA:  Water Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  2901-9     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2010 Elsevier Ltd. All rights reserved.
Affiliation:
Advanced Water Management Centre (AWMC), The University of Queensland, St Lucia, Brisbane, QLD 4072, Australia.
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MeSH Terms
Descriptor/Qualifier:
Aerobiosis / drug effects*
Bacteria, Aerobic / growth & development,  metabolism*
Glycogen / metabolism
Nitrous Acid / pharmacology*
Polyphosphates / metabolism
Chemical
Reg. No./Substance:
0/Polyphosphates; 7782-77-6/Nitrous Acid; 9005-79-2/Glycogen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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