Document Detail

The effect of exhaustive exercise on salivary immunoglobulin A.
MedLine Citation:
PMID:  1293425     Owner:  NLM     Status:  MEDLINE    
The purpose of this study was to examine salivary immunoglobulin A (s-IgA) responses to exhaustive exercise. Twenty-nine, college age (means +/- SD = 21.45 +/- 3.1 yrs; range 18-29 yrs) moderately active males (running < 10 miles per week) performed an incremental treadmill test to exhaustion. Unstimulated salivary samples, collected before as well as immediately and one hour following the test, were analyzed for s-IgA using an enzyme-linked immunosorbent assay (ELISA). Mean s-IgA levels decreased significantly (24.4%, p < 0.05) immediately following the maximal test, and remained depressed (16.9%) one hour after the test. Of the 29 subjects, five exhibited an increase (range = 1.3 to 53.3%) in s-IgA following the exercise bout. The results of this study suggest that exhaustive exercise may temporarily reduce salivary IgA levels.
S L McDowell; R A Hughes; R J Hughes; D J Housh; T J Housh; G O Johnson
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of sports medicine and physical fitness     Volume:  32     ISSN:  0022-4707     ISO Abbreviation:  J Sports Med Phys Fitness     Publication Date:  1992 Dec 
Date Detail:
Created Date:  1993-04-02     Completed Date:  1993-04-02     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0376337     Medline TA:  J Sports Med Phys Fitness     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  412-5     Citation Subset:  IM    
Center for Youth Fitness and Sports Research, University of Nebraska-Lincoln, Lincoln.
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MeSH Terms
Enzyme-Linked Immunosorbent Assay
Exercise Test
Immunoglobulin A / chemistry*
Saliva / chemistry*
Specimen Handling
Reg. No./Substance:
0/Immunoglobulin A

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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