Document Detail


The effect of exercise and zinc supplement on the hematological parameters in rats.
MedLine Citation:
PMID:  7505095     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study evaluates the consequences of a session of intensive short-duration exercise and Zn supplementation on different hematological variables. Forty male Wistar rats were divided into four groups (n = 10): the first nonsupplemented, maintained at rest (R); the second nonsupplemented, undergoing exercise (E); the third supplemented with Zn, kept at rest (ZnR); and the fourth supplemented with Zn, undergoing exercise (ZnE). Zinc supplements (200 ppm) were given in drinking water. The exercise consisted of a single session of swimming until exhaustion. At rest, RBC, Hb, and Hto fell (p < 0.05), whereas red cell indices, MCV, and MCH rose (p < 0.05) in +ZnR compared with R; MCHC remained unchanged (ZnR vs R). After exercise, RBC, Hb, and Hto increased significantly in E and in ZnE compared with R and ZnR, respectively. In addition, RBC and Hb were lower (p < 0.01) in ZnE compared with E; however, MCV and MCH were higher (p < 0.05) in the group ZnE vs E. With respect to white blood cells--leukocytes (WBC), lymphocytes (LYMPH), and neutrophils (NEUT)--no significant differences were observed between groups at rest (ZnR vs R). WBC and LYMPH increased significantly in E with respect to the rest situation (E vs R), but this did not happen in supplemented animals (ZnE vs ZnR). Level of pH decreased after exercise both in E and in ZnE, but the fall was lower in the latter. We believe that a single session of swimming until exhaustion leads to an increase in RBC, Hb, and Hto without causing changes in MCV, MCH, and MCHC.(ABSTRACT TRUNCATED AT 250 WORDS)
Authors:
A Cordova; F J Navas; J F Escanero
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Biological trace element research     Volume:  39     ISSN:  0163-4984     ISO Abbreviation:  Biol Trace Elem Res     Publication Date:  1993 Oct 
Date Detail:
Created Date:  1994-01-25     Completed Date:  1994-01-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7911509     Medline TA:  Biol Trace Elem Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  13-20     Citation Subset:  IM    
Affiliation:
Department of Physiology and Biochemistry, University of Valladolid, School of Physiotherapy, Soria, Spain.
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MeSH Terms
Descriptor/Qualifier:
Acidosis / etiology,  prevention & control
Animals
Blood Cells / drug effects*
Erythrocytes / drug effects
Male
Physical Conditioning, Animal*
Rats
Rats, Wistar
Zinc / pharmacology*
Chemical
Reg. No./Substance:
7440-66-6/Zinc

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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