Document Detail

The effect of exercise on leptin, insulin, cortisol and lipid profiles in obese children.
MedLine Citation:
PMID:  19930853     Owner:  NLM     Status:  MEDLINE    
This prospective, randomized study investigated the effect of exercise on leptin, insulin, cortisol and lipid profiles in obese children. A total of 40 obese boys aged 10 - 12 years with a body mass index (BMI) >or= 30 kg/m(2) were randomly separated into an exercise group (n = 20) that underwent a 12-week aerobic exercise programme and a non-exercise (control) group (n = 20). The BMI, low-density lipoprotein, cortisol, leptin and insulin levels were significantly lower in the exercise group after 12 weeks compared with baseline values, whereas high-density lipoprotein levels were significantly higher. In contrast, in the control group, low-density lipoprotein, cortisol and leptin levels were significantly higher after 12 weeks compared with baseline values while high-density lipoprotein levels were significantly lower. These findings indicate the importance of regular exercise in the regulation of body weight and protection against cardiovascular risk factors in obese children.
Kursat Karacabey
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Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  The Journal of international medical research     Volume:  37     ISSN:  0300-0605     ISO Abbreviation:  J. Int. Med. Res.     Publication Date:    2009 Sep-Oct
Date Detail:
Created Date:  2009-11-25     Completed Date:  2010-03-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0346411     Medline TA:  J Int Med Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  1472-8     Citation Subset:  IM    
Higher School of Physical Education and Sports, Gaziantep University, Gaziantep, Turkey.
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MeSH Terms
Body Mass Index
Case-Control Studies
Enzyme-Linked Immunosorbent Assay
Exercise Therapy*
Hydrocortisone / blood*
Hypoglycemic Agents / blood
Insulin / blood*
Leptin / blood*
Lipids / blood*
Obesity / physiopathology,  therapy*
Prospective Studies
Reg. No./Substance:
0/Hypoglycemic Agents; 0/Leptin; 0/Lipids; 11061-68-0/Insulin; 50-23-7/Hydrocortisone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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