| The effect of exercise and anabolic steroids on the mechanical properties and crimp morphology of the rat tendon. | |
| | |
MedLine Citation:
|
PMID: 3377099 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The administration of anabolic steroids is believed to be widespread among athletes, but convincing evidence relating to the beneficial effect of such compounds on collagenous structures of the locomotor system is not available. Since it has not been possible to analyze relevant human tissue, an animal model was used to investigate the change in particular mechanical and morphological properties of rat tendon after a period of controlled exercise, with or without anabolic steroid supplementation. A significant difference (P less than 0.001) was found between the crimp angles and lengths of collagen fibrils and theoretical toe limit strains of the four groups under study. No other significant differences (P greater than 0.05) were observed. Controlled exercise and anabolic steroid administration produced the greatest change in crimp parameters and the largest theoretical toe limit strain. This implies that muscle contraction will be greater for a given stress and thus alter the normal biomechanics of limb movement. Further studies are required to determine more definitively the effects of anabolic steroids on a connective tissue such as tendon. |
| | |
Authors:
|
T O Wood; P H Cooke; A E Goodship |
Related Documents
:
|
13678439 - Synergistic action of growth factors and dynamic loading for articular cartilage tissue... 16849829 - Adaptation of the tendon to mechanical usage. 20646109 - Effects of growth and exercise on composition, structural maturation and appearance of ... 10656049 - Thermomechanical analysis of collagen crosslinking in the developing ovine thoracic aorta. 21346019 - Varying the cause of a challenge to exercise identity behavior: reactions of individual... 2300349 - Minimum extension and appropriate topographic position of tissue destruction for treatm... 1996429 - Techniques for radioactive decontamination in nuclear medicine. 7810029 - Estimation of aerobic and anaerobic metabolism in isometric forearm exercise. 22292849 - Life style in persons with functional gastrointestinal disorders - large-scale internet... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: The American journal of sports medicine Volume: 16 ISSN: 0363-5465 ISO Abbreviation: Am J Sports Med Publication Date: 1988 Mar-Apr |
Date Detail:
|
Created Date: 1988-07-14 Completed Date: 1988-07-14 Revised Date: 2008-11-21 |
Medline Journal Info:
|
Nlm Unique ID: 7609541 Medline TA: Am J Sports Med Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 153-8 Citation Subset: IM |
Affiliation:
|
Comparative Orthopaedic Research Group, University of Bristol, England. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Achilles Tendon
/
drug effects*,
pathology,
physiopathology Anabolic Agents / pharmacology* Animals Collagen / physiology Elasticity Male Physical Exertion* Rats Rats, Inbred Strains Stress, Mechanical |
| Chemical | |
Reg. No./Substance:
|
0/Anabolic Agents; 9007-34-5/Collagen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: An in vivo analysis of the effect of transcutaneous electrical stimulation of the quadriceps and ham...
Next Document: Tibial plateau fractures in alpine skiing.