| The effect of estrogen and gestagen on the mucus production of human endocervical cells: a histochemical study. | |
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MedLine Citation:
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PMID: 6215266 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The effect of hormonal stimulation on the intracellular mucus production of the endocervical cells was histochemically and morphometrically investigated. Twenty-seven cervixes from patients who had received estrogen or gestagen prior to hysterectomy were examined. "Upper" versus "lower" cervix and "small" versus "large" crypts were compared in both groups of patients. The histochemical analysis of mucins within the cells was based mainly on the combined alcian blue/periodic acid Schiff (AB/PAS) techniques at various pH levels. A semiquantitative estimation using cell counts and statistical evaluations was done for each staining method. The results indicate that sex hormones influence the chemical composition of endocervical mucus production. In addition, the nature of the intracellular mucus varies with the cryptal size and location within the cervical canal. |
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Authors:
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E Gaton; L Zejdel; D Bernstein; M Glezerman; B Czernobilsky; V Insler |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Fertility and sterility Volume: 38 ISSN: 0015-0282 ISO Abbreviation: Fertil. Steril. Publication Date: 1982 Nov |
Date Detail:
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Created Date: 1982-12-21 Completed Date: 1982-12-21 Revised Date: 2009-11-19 |
Medline Journal Info:
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Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 580-5 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Alcian Blue Cervix Mucus / metabolism* Cervix Uteri / cytology, drug effects, metabolism* Estrogens / pharmacology* Ethinyl Estradiol / pharmacology Female Histocytochemistry Humans Medroxyprogesterone / analogs & derivatives, pharmacology Medroxyprogesterone Acetate Mucins / analysis Periodic Acid-Schiff Reaction Progestins / pharmacology* |
| Chemical | |
Reg. No./Substance:
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0/Estrogens; 0/Mucins; 0/Progestins; 12040-44-7/Alcian Blue; 520-85-4/Medroxyprogesterone; 57-63-6/Ethinyl Estradiol; 71-58-9/Medroxyprogesterone Acetate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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