Document Detail


The effect of early treatment at the initial stage 3 moderate phase of retinopathy of prematurity on severe retinal changes.
MedLine Citation:
PMID:  16187040     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To compare the outcome of early treatment at the initial stage 3 moderate phase of retinopathy of prematurity (ROP) with that at prethreshold ROP. METHODS: The outcome of treatment of 117 very-low-birth-weight infants was reviewed. Sixty-eight infants underwent their first treatment at prethreshold ROP (group A). The other 49 infants underwent their first treatment at the initial stage 3 moderate phase of ROP (pre-prethreshold ROP) (group B). The first treatment was performed by laser photocoagulation or cryotherapy. Eleven clinical variables were included in the evaluation of the two groups. The outcome of treatment of the two groups was compared as favorable or unfavorable. Logistic regression analysis was performed to assess the relation between each independent variable and an unfavorable outcome. RESULTS: The extent of contiguous stage 3 moderate ROP and that of cumulative stage 3 moderate ROP were significantly smaller in group B. There were nine unfavorable outcomes in group A, but none in group B. Logistic regression analysis showed that the extent of cumulative stage 3 moderate ROP and the presence of zone 1 retinopathy were major predictive factors for unfavorable outcome in the treatment of very-low-birth-weight infants. CONCLUSION: Early treatment at the initial stage 3 moderate phase of ROP decreases the occurrence of severe retinal changes.
Authors:
Yoshikazu Hatsukawa; Nami Ueki; Tomoko Yamagishi; Hiroyuki Kitajima
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Japanese journal of ophthalmology     Volume:  49     ISSN:  0021-5155     ISO Abbreviation:  Jpn. J. Ophthalmol.     Publication Date:    2005 Sep-Oct
Date Detail:
Created Date:  2005-09-27     Completed Date:  2005-10-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0044652     Medline TA:  Jpn J Ophthalmol     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  391-6     Citation Subset:  IM    
Affiliation:
Department of Ophthalmology, Osaka Medical Center and Research Institute for Maternal and Child Health, Osaka, Japan. hatsu@mch.pref.osaka.jp
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MeSH Terms
Descriptor/Qualifier:
Cryotherapy*
Female
Humans
Infant
Infant, Low Birth Weight
Infant, Newborn
Laser Coagulation*
Male
Retinopathy of Prematurity / classification,  surgery*
Treatment Outcome
Visual Acuity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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