| The effect of dose on maternal-foetal transfer of fluoride in rabbits. | |
MedLine Citation:
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PMID: 1854264 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Placental transfer of fluoride was investigated by fluoride determination in the bones and teeth of newborn rabbits whose mothers had been treated with fluoride during pregnancy. The mothers were given doses of 0, 0.10, 0.52 and 1.05 mmol fluoride per kg body weight as sodium fluoride, from the 16th day after conception to the end of pregnancy. All the doses produced a significant increase of fluoride level in the bones and teeth of newborn rabbits, indicating that the placenta was no barrier for the passage of fluoride. |
Authors:
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M Nedeljković; V Matović |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Arhiv za higijenu rada i toksikologiju Volume: 42 ISSN: 0004-1254 ISO Abbreviation: Arh Hig Rada Toksikol Publication Date: 1991 Mar |
Date Detail:
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Created Date: 1991-08-21 Completed Date: 1991-08-21 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0373100 Medline TA: Arh Hig Rada Toksikol Country: YUGOSLAVIA |
Other Details:
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Languages: eng Pagination: 43-6 Citation Subset: IM |
Affiliation:
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Department of Toxicological Chemistry, School of Pharmacy, University of Belgrade, Yugoslavia. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Animals, Newborn / metabolism Bone and Bones / metabolism Dose-Response Relationship, Drug Female Maternal-Fetal Exchange* Pregnancy Rabbits Sodium Fluoride / administration & dosage, pharmacokinetics* Tooth / metabolism |
| Chemical | |
Reg. No./Substance:
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7681-49-4/Sodium Fluoride |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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