Document Detail


The effect of displacement on the mechanical properties of human cadaver subsynovial connective tissue.
MedLine Citation:
PMID:  22573580     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The subsynovial connective tissue (SSCT) in the carpal tunnel may participate in the origin of carpal tunnel syndrome (CTS), yet material properties of the SSCT have not been well-characterized. We investigated the response of the SSCT to repeated ramp stretch tests. Eight human cadaver wrists were used. The physiological excursion of the flexor digitorum superficialis of the third digit (FDS 3) was measured, starting from a neutral position to maximal flexion of the metacarpophalangeal and proximal interphalangeal joints. The FDS 3 tendon was pulled to 40%, 60%, 90%, and 120% of the physiological excursion. Two "ramp stretch" cycles were performed at every excursion level, except for 120% of excursion, where three cycles were performed. The ratio of energy absorbed between the second (E2) and first (E1) ramp stretch was 0.94 (SD = 0.07) for 60%, 0.84 (SD = 0.11) for 90%, and 0.68 (SD = 0.11) for 120% of the physiological excursion. A significant decrease occurred in energy absorbed after the first ramp stretch cycle at 90% and 120% of the physiological excursion, which was not seen at 60%. Our data are consistent with a stepwise damage occurring in the SSCT. Furthermore, the damage seems to initiate within the physiological range of tendon excursion. This finding may be important in understanding the pathophysiology of conditions that are associated with SSCT pathology, such as carpal tunnel syndrome.
Authors:
Matthias Vanhees; Yutaka Morizaki; Andrew R Thoreson; Dirk Larson; Chunfeng Zhao; Kai-Nan An; Peter C Amadio
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2012-05-09
Journal Detail:
Title:  Journal of orthopaedic research : official publication of the Orthopaedic Research Society     Volume:  30     ISSN:  1554-527X     ISO Abbreviation:  J. Orthop. Res.     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-10-04     Completed Date:  2012-12-17     Revised Date:  2013-11-06    
Medline Journal Info:
Nlm Unique ID:  8404726     Medline TA:  J Orthop Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1732-7     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Orthopaedic Research Society.
Affiliation:
Biomechanics Laboratory, Division of Orthopedic Research, Mayo Clinic, Rochester, MN 55905-0001, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Biomechanics
Carpal Tunnel Syndrome / etiology,  physiopathology*
Connective Tissue / physiology*
Female
Humans
Male
Middle Aged
Wrist Joint / physiology*
Grant Support
ID/Acronym/Agency:
R01 AR049823/AR/NIAMS NIH HHS; R01AR49823/AR/NIAMS NIH HHS
Comments/Corrections

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