| The effect of different nutritional states on cell-mediated cytotoxicity. | |
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MedLine Citation:
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PMID: 2373524 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We have studied the effect of acute short-term starvation (in 9 patients) and of prolonged caloric deprivation (in 10 patients with anorexia nervosa), on cell-mediated cytotoxicity (CMC). CMC became severely depressed after six days on a very low caloric diet (1.2 +/- 1.4 vs. 7.0 +/- 2.9 lytic units/10(6) cells; P less than 0.01). CMC was also low in our patients with anorexia nervosa compared to a matched control group (3.3 +/- 1.7 vs. 10.0 +/- 3.0 lytic units/10(6) cells; P less than 0.01) and increased in most of the patients studied (five cases) after the first 3-4 weeks of refeeding in correlation with weight gain. Dietary deprivation may lead to a significant impairment in cell-mediated cytotoxicity, which appears to be reversible after refeeding. |
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Authors:
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N Vaisman; T Hahn; Y Dayan; A Schattner |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Immunology letters Volume: 24 ISSN: 0165-2478 ISO Abbreviation: Immunol. Lett. Publication Date: 1990 Mar-Apr |
Date Detail:
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Created Date: 1990-08-29 Completed Date: 1990-08-29 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7910006 Medline TA: Immunol Lett Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 37-41 Citation Subset: IM |
Affiliation:
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Department of Paediatrics, Kaplan Hospital, Rehovot, Israel. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Analysis of Variance Anorexia Nervosa / immunology* Body Weight Cytotoxicity, Immunologic / immunology* Energy Intake Female Hela Cells Humans Male Middle Aged Nutritional Status* Starvation / immunology |
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