Document Detail

The effect of different high-pass filter settings on peak latencies in the event-related potentials of schizophrenics, patients with Parkinson's disease and controls.
MedLine Citation:
PMID:  1375887     Owner:  NLM     Status:  MEDLINE    
Eighteen schizophrenic patients, 16 patients with idiopathic Parkinson's disease, and the same numbers of age, sex and education matched controls were examined with oddball experiments for the generation of P3. Individual averages were high-pass filtered at different cut-off frequencies with single-pole digital filters with equivalent analogue Butterworth filter profiles. The purpose of this procedure was to simulate analogue high-pass filters used in clinical studies from different centres and to examine their potential effect on group differences. Increasing high-pass filters resulted in a phase lead for all peaks examined (N1, P2, N2, P3). The only group differences were found for P3, which showed a greater phase lead in controls than in the patient groups, usually resulting in a more pronounced group difference. Similar wave forms and filter properties could be modelled by synthetic wave forms consisting of sine waves of different frequencies.
K P Ebmeier; M Glabus; D D Potter; E A Salzen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Electroencephalography and clinical neurophysiology     Volume:  84     ISSN:  0013-4694     ISO Abbreviation:  Electroencephalogr Clin Neurophysiol     Publication Date:    1992 May-Jun
Date Detail:
Created Date:  1992-07-09     Completed Date:  1992-07-09     Revised Date:  2008-09-09    
Medline Journal Info:
Nlm Unique ID:  0375035     Medline TA:  Electroencephalogr Clin Neurophysiol     Country:  IRELAND    
Other Details:
Languages:  eng     Pagination:  280-7     Citation Subset:  IM    
MRC Brain Metabolism Unit, Royal Edinburgh Hospital, U.K.
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MeSH Terms
Acoustic Stimulation
Analysis of Variance
Evoked Potentials / physiology*
Parkinson Disease / physiopathology*
Reaction Time / physiology*
Schizophrenia / physiopathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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