| The effect of different doses of methisoprinol on the percentage of CD4+ and CD8+ T lymphocyte subpopulation and the antibody titers in pigeons immunised against PPMV-1. | |
| | |
MedLine Citation:
|
PMID: 21957729 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
|
As immunosuppression in pigeons is common and results in reduced post-vaccination immunity and lower health status of the birds, studies have been taken up aimed at evaluation of the effect of three doses of methisoprinol on the percentage of CD4+ and CD8+ T lymphocyte subpopulation in peripheral blood and in the spleen and the titre of anti-NDV antibodies in the serum of pigeons in four groups (A, B, C, D), with 20 birds each. Pigeons in each group were immunised against paramyxovirosis at week 6 and 9 of life. Water for injection (group A - control) or methisoprinol at 100 mg/kg of body weight (group B), 200 mg/kg of body weight (group C) and 600 mg/kg of body weight (group D) was administered intramuscularly for 3 days before each vaccination. The immunological analyses were carried out by flow cytometry and the ELISA test. The findings indicate that methisoprinol administered intramuscularly at 100 and 200 mg/kg of body weight for 3 successive days before vaccination against paramyxovirosis mainly stimulates the mechanisms of non-specific humoral and cellular immunity, which is indicated by a higher percentage of the subpopulation of CD4+ T lymphocytes in peripheral blood and in the spleen and a higher titre of anti-NDV antibodies. |
| | |
Authors:
|
T Stenzel; B Tykałowski; M Smiałek; A Koncicki; A Kwiatkowska-Stenzel |
Related Documents
:
|
2138489 - Neuromuscular block with doxacurium (bw a938u) in patients with normal or absent renal ... 3755639 - Comparison of the effects of succinylcholine and atracurium on intracranial pressure in... 2571699 - Interactions of apomorphine and a novel neuroleptic dibenzodioxazocine derivative, as e... 7689399 - Effects of krn2391, nicorandil and diltiazem on the changes in the electrocardiogram ca... 6411799 - Influence of experimental hepatic impairment on the toxicokinetics and the anticholines... 2574099 - Vecuronium infusions for prolonged muscle relaxation in the intensive care unit. 19775899 - Characteristics of a new polymer gel for high-dose gradient dosimetry using a micro opt... 8566489 - Metabolism and testicular toxicity of 1,3-dinitrobenzene in the rat: effect of route of... 11697769 - Seminal toxicity of nickel sulfate in mice. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Polish journal of veterinary sciences Volume: 14 ISSN: 1505-1773 ISO Abbreviation: Pol J Vet Sci Publication Date: 2011 |
Date Detail:
|
Created Date: 2011-09-30 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101125473 Medline TA: Pol J Vet Sci Country: Poland |
Other Details:
|
Languages: eng Pagination: 367-71 Citation Subset: IM |
Affiliation:
|
Department of Poultry Diseases, Faculty of Veterinary Medicine, University of Warmia and Mazury, Oczapowskiego 13, 10-957 Olsztyn, Poland. ptasiarz@wp.pl |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Effect of combined administration of enterocin 4231 and sage in rabbits.
Next Document: The effect of interval versus continuous exercise on plasma leptin and ghrelin concentration in youn...