Document Detail


The effect of dietary n-6:n-3 ratio and sex on broiler breeder immunity.
MedLine Citation:
PMID:  21934002     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
A study was conducted with male and female adult broiler breeders to determine the effect of feeding a fish oil supplement on selected immune activities. The fish oil was added to the diet such that the n-6:n-3 ratios could meet certain levels. Four hundred Ross 308 broiler breeder hens and 48 Ross 308 broiler breeder roosters at 30 wk of age were randomly assigned to diets containing 3.5% fat with n-6:n-3 ratios of 4, 6, 8, and 16. As a measure of cell-mediated immunity, thickness of the toe web was measured at 4, 8, 24, and 48 h after injection of phytohemagglutinin-P (PHA-P) at 32 wk of age. Total antibodies were quantified 6 and 9 d after the injection of SRBC at 33 wk of age. Blood lymphocyte proliferation was assayed after in vitro stimulation with PHA-P at 34 wk of age. The fatty acid profile of the spleen was determined in roosters. The effects of dietary n-6:n-3 ratios on total antibodies and in vitro lymphocyte proliferation were not significant (P > 0.05). However, the birds fed diets containing an n-6:n-3 ratio of 8 showed the greatest toe web thickness (P < 0.05). Total antibodies in hens at 9 d after SRBC injection were significantly greater than those of roosters. Conversely, toe web thickness in roosters was greater than that of hens (P < 0.05). Although the increase in the dietary n-6:n-3 ratio of polyunsaturated fatty acids significantly decreased the concentrations of eicosapentaenoic acid, docosahexaenoic acid, total n-3 (P < 0.05), linoleic acid, arachidonic acid, and total n-6, the n-6:n-3 fatty acid ratios of the entire spleen were significantly increased (P < 0.05). Results indicated that under the conditions of this study, the n-6:n-3 ratios seemed to influence the toe web response to PHA-P, but not the antibody response or the cell proliferation response in vitro.
Authors:
A Khatibjoo; H Kermanshahi; A Golian; M Zaghari
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Poultry science     Volume:  90     ISSN:  0032-5791     ISO Abbreviation:  Poult. Sci.     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-09-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401150     Medline TA:  Poult Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2209-16     Citation Subset:  IM    
Affiliation:
The Excellence Center for Animal Sciences and Department of Animal Science, Faculty of Agriculture, Ferdowsi University of Mashhad, Mashhad, Iran 91775-1163; and.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Genetic evaluation of carcass composition and fat deposition in Japanese quail.
Next Document:  Antimicrobial activity of butyrate glycerides toward Salmonella Typhimurium and Clostridium perfring...