Document Detail

The effect of dietary copper supplementation on fatty acid profile and oxidative stability of adipose depots in Boer x Spanish goats.
MedLine Citation:
PMID:  17998427     Owner:  NLM     Status:  MEDLINE    
A feeding trial was designed to examine the effects of copper sulfate pentahydrate (CuSO(4).5H(2)O) on the fatty acid composition and oxidative stability in muscle and adipose tissues of Boer x Spanish goat kids. Fifteen (n = 5 per treatment) goats were fed 0, 100, or 200 mg of supplemental Cu per day as copper sulfate for 98 d. The animals were slaughtered, and LM, s.c. adipose from the sternal region, and mesenteric adipose tissues were collected. Total lipids were extracted with chloroform:methanol (2:1), methylated and isolated via GLC from all tissues. The subsequent peaks were then positively identified by mass spectrometry. Thiobarbituric acid-reactive substances were measured also. In s.c. adipose, dietary Cu significantly decreased C14:0 (P = 0.03) and C16:0 (P = 0.01). In muscle, C15:0 (P = 0.03) was linearly increased by Cu. Dietary Cu supplementation did not influence oxidative stability in goat muscle or s.c. adipose. Copper supplementation at 200 mg/d resulted in a significant increase in malondialdehyde in mesenteric adipose (P = 0.01) compared with the 0 or 100 mg/d groups. These results indicate that lipid composition may differ from depot to depot and that depending on the depot, dietary Cu seems to elicit a variable response on the fatty acid composition.
K A Cummins; S G Solaiman; W G Bergen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2007-11-12
Journal Detail:
Title:  Journal of animal science     Volume:  86     ISSN:  1525-3163     ISO Abbreviation:  J. Anim. Sci.     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-01-24     Completed Date:  2008-04-04     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8003002     Medline TA:  J Anim Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  390-6     Citation Subset:  IM    
Department of Animal Sciences, Auburn University, Auburn, AL 36849, USA.
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MeSH Terms
Adipose Tissue / metabolism*
Animal Feed
Animal Nutritional Physiological Phenomena
Animals, Newborn / growth & development,  metabolism
Body Composition / drug effects
Copper / administration & dosage,  pharmacology*
Crosses, Genetic
Dietary Supplements
Dose-Response Relationship, Drug
Fatty Acids / analysis,  metabolism*
Gas Chromatography-Mass Spectrometry / veterinary
Goats / growth & development,  metabolism*
Muscle, Skeletal / metabolism*
Random Allocation
Thiobarbituric Acid Reactive Substances / analysis
Reg. No./Substance:
0/Fatty Acids; 0/Thiobarbituric Acid Reactive Substances; 7440-50-8/Copper

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