| The effect of dexamethasone on postoperative vomiting after tonsillectomy. | |
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MedLine Citation:
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PMID: 11226091 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In this double-blinded, randomized, placebo-controlled study, we assessed the effect of dexamethasone 0.5 mg/kg IV administered preoperatively in 110 children 2-12 yr old, undergoing electrodissection adenotonsillectomy, using a standardized anesthetic technique. The incidence of early and late vomiting, the time to first oral intake, the quality of oral intake, the satisfaction scores, and the duration of IV hydration were compared in both groups. The overall incidence of vomiting, as well as the incidence of late vomiting, was significantly less in the Dexamethasone group as compared with the Saline group (23% and 19% vs 51% and 34%, respectively). The time to first oral intake and the duration of IV hydration were shorter in the Dexamethasone group compared with the Saline group (P < 0.05). The quality of oral intake and the satisfaction scores were better in the Dexamethasone group than in the Saline group (P < 0.05). This report confirms the beneficial effect of IV dexamethasone on both vomiting and oral intake in children undergoing electrodissection adenotonsillectomy. IMPLICATIONS: In this double-blinded, placebo-controlled study, we examined the efficacy of a single dose of dexamethasone 0.5 mg/kg IV on posttonsillectomy vomiting and oral intake in children 2-12 yr old. Dexamethasone significantly decreased the incidence of postoperative vomiting during the first 24 h, shortened the time to the first oral intake and the duration of IV hydration, and improved the quality of oral intake and the satisfaction scores of the patients. |
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Authors:
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M T Aouad; S S Siddik; L B Rizk; G M Zaytoun; A S Baraka |
Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Anesthesia and analgesia Volume: 92 ISSN: 0003-2999 ISO Abbreviation: Anesth. Analg. Publication Date: 2001 Mar |
Date Detail:
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Created Date: 2001-03-06 Completed Date: 2001-03-22 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 1310650 Medline TA: Anesth Analg Country: United States |
Other Details:
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Languages: eng Pagination: 636-40 Citation Subset: AIM; IM |
Affiliation:
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Department of Anesthesiology, American University of Beirut, Beirut, Lebanon. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Age Factors Antiemetics / therapeutic use* Child Child, Preschool Dexamethasone / therapeutic use* Female Humans Male Postoperative Nausea and Vomiting / prevention & control* Tonsillectomy / adverse effects* |
| Chemical | |
Reg. No./Substance:
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0/Antiemetics; 50-02-2/Dexamethasone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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