Document Detail

The effect of delivery on umbilical arterial cord blood gases and lipid peroxides: comparison of vaginal delivery and cesarean section.
MedLine Citation:
PMID:  12519045     Owner:  NLM     Status:  MEDLINE    
Umbilical arterial blood gas analysis is the most objective method to assess fetal well being at birth, is the gold standard assessment of uteroplacental function and fetal oxygenation/acid-base status at birth, and it excludes the diagnosis of birth asphyxia in approximately 80% of depressed newborns at term. This study was designed to determine the effect of the type of delivery on umbilical cord blood gases and on free radical activity together with antioxidation in the fetus. Ninety-six pregnant women between 37 and 42 weeks of gestation were included to the study and randomly assigned to the one of three groups: Group 1 (n = 40) were vaginally delivered, Group 2 (n = 26) had cesarean section with epidural anaesthesia, and Group 3 (n = 30) had cesarean section under general anaesthesia. Umbilical artery blood gas analysis was performed just after the delivery of the fetus together with melondealdehyde and glutathione. The umbilical arterial PO2 was found to be higher in Group 3, and malondealdehyde and glutathione levels were lower in newborns of Group 2. It can be concluded that cesarean section with epidural anaesthesia is safer when lipid peroxides are concerned.
S Pence; H Kocoglu; O Balat; A Balat
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Clinical and experimental obstetrics & gynecology     Volume:  29     ISSN:  0390-6663     ISO Abbreviation:  Clin Exp Obstet Gynecol     Publication Date:  2002  
Date Detail:
Created Date:  2003-01-09     Completed Date:  2003-04-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7802110     Medline TA:  Clin Exp Obstet Gynecol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  212-4     Citation Subset:  IM    
Department of Physiology, University of Gaziantep, Faculty of Medicine, Gaziantep, Turkey.
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MeSH Terms
Anesthesia, Epidural
Anesthesia, General
Anesthesia, Obstetrical
Carbon Dioxide / blood*
Cesarean Section*
Delivery, Obstetric*
Fetal Blood / chemistry*
Lipid Peroxides / blood*
Oxygen / blood*
Partial Pressure
Reg. No./Substance:
0/Lipid Peroxides; 124-38-9/Carbon Dioxide; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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