| The effect of delivery on umbilical arterial cord blood gases and lipid peroxides: comparison of vaginal delivery and cesarean section. | |
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MedLine Citation:
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PMID: 12519045 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Umbilical arterial blood gas analysis is the most objective method to assess fetal well being at birth, is the gold standard assessment of uteroplacental function and fetal oxygenation/acid-base status at birth, and it excludes the diagnosis of birth asphyxia in approximately 80% of depressed newborns at term. This study was designed to determine the effect of the type of delivery on umbilical cord blood gases and on free radical activity together with antioxidation in the fetus. Ninety-six pregnant women between 37 and 42 weeks of gestation were included to the study and randomly assigned to the one of three groups: Group 1 (n = 40) were vaginally delivered, Group 2 (n = 26) had cesarean section with epidural anaesthesia, and Group 3 (n = 30) had cesarean section under general anaesthesia. Umbilical artery blood gas analysis was performed just after the delivery of the fetus together with melondealdehyde and glutathione. The umbilical arterial PO2 was found to be higher in Group 3, and malondealdehyde and glutathione levels were lower in newborns of Group 2. It can be concluded that cesarean section with epidural anaesthesia is safer when lipid peroxides are concerned. |
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Authors:
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S Pence; H Kocoglu; O Balat; A Balat |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Clinical and experimental obstetrics & gynecology Volume: 29 ISSN: 0390-6663 ISO Abbreviation: Clin Exp Obstet Gynecol Publication Date: 2002 |
Date Detail:
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Created Date: 2003-01-09 Completed Date: 2003-04-03 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7802110 Medline TA: Clin Exp Obstet Gynecol Country: Italy |
Other Details:
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Languages: eng Pagination: 212-4 Citation Subset: IM |
Affiliation:
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Department of Physiology, University of Gaziantep, Faculty of Medicine, Gaziantep, Turkey. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anesthesia, Epidural Anesthesia, General Anesthesia, Obstetrical Carbon Dioxide / blood* Cesarean Section* Delivery, Obstetric* Female Fetal Blood / chemistry* Humans Lipid Peroxides / blood* Oxygen / blood* Partial Pressure Pregnancy |
| Chemical | |
Reg. No./Substance:
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0/Lipid Peroxides; 124-38-9/Carbon Dioxide; 7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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