Document Detail

The effect of deep sclerectomy on intraocular pressure of normal-tension glaucoma patients: 1-year results.
MedLine Citation:
PMID:  19775310     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To study the intraocular pressure (IOP)-reducing effect of deep sclerectomy on normal-tension glaucoma (NTG) patients. METHODS: We retrospectively analysed 21 eyes of 18 consecutive NTG patients who had undergone deep sclerectomy with mitomycin-C and a collagen implant. RESULTS: Median (range) preoperative IOP was 15.1 mmHg (9.3-20.8) and median follow-up time 13 months (12-18). At the 1-year follow-up visit, median IOP was significantly (P < 0.001) reduced to 10.5 mmHg (4-15) with median IOP reduction from preoperative values of 37% (12-78). Laser goniopuncture was performed in 10 eyes (48%) 1-16 months postoperatively. After 13 months' follow-up, a complete success at 20%, 25% and 30% IOP reduction levels was achieved in 67%, 62% and 52% of eyes, respectively. Few complications were encountered, but these included reduced visual acuity, problems with conjunctiva, microperforation, hyphaema, Dellen formation and encapsulated bleb. We encountered no complications related to postoperative hypotony. CONCLUSION: Deep sclerectomy with a collagen implant and mitomycin-C was a safe and effective method for reducing IOP in NTG patients during 1-year follow-up.
Sakari Suominen; Mika Harju; Tapio Ihanam?ki; Eija Vesti
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-09-23
Journal Detail:
Title:  Acta ophthalmologica     Volume:  88     ISSN:  1755-3768     ISO Abbreviation:  Acta Ophthalmol     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-04-27     Completed Date:  2010-05-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101468102     Medline TA:  Acta Ophthalmol     Country:  England    
Other Details:
Languages:  eng     Pagination:  27-32     Citation Subset:  IM    
Department of Ophthalmology, Helsinki University Central Hospital, Finland.
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MeSH Terms
Absorbable Implants
Anterior Chamber / surgery
Collagen / administration & dosage
Conjunctival Diseases / etiology
Follow-Up Studies
Hyphema / etiology
Intraocular Pressure*
Intraoperative Care
Intraoperative Complications
Laser Therapy
Low Tension Glaucoma / physiopathology*,  surgery*
Middle Aged
Mitomycin / administration & dosage
Postoperative Complications
Postoperative Period
Retrospective Studies
Sclerostomy / adverse effects,  methods*
Visual Acuity
Reg. No./Substance:
50-07-7/Mitomycin; 9007-34-5/Collagen

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